SCHEMBL339890

SCHEMBL339890

O=C1C=C(c2ccc(C(=O)c3ccccc3)cc2)C(=O)N1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.49
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
LMNA P02545 1/20 0.49
MAPT P10636 1/20 0.49
ALDH1A1 P00352 3/20 0.47
SRD5A2 P31213 1/20 0.46
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
GAA P10253 1/20 0.42
ATM Q13315 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
MAPK13 O15264 1/20 0.41
MAPK12 P53778 1/20 0.41
MAPK11 Q15759 1/20 0.41
MAPK14 Q16539 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29393770 0.93 LMNA (0.37) RAB9AMEN1KMT2ALMNAMAPT
N-Ethylmaleimide SCHEMBL15130052 0.84 ALDH1A1 (0.38) RAB9AMEN1KMT2ALMNAMAPT
SCHEMBL534775 0.84 TSHR (0.44) ALDH1A1SRD5A2CA12CA1CA2
SCHEMBL29395801 0.84 HPGD (0.38) RAB9AMEN1KMT2ALMNAMAPT
SCHEMBL30824732 0.84 SRD5A2 (0.44) RAB9AMEN1KMT2ALMNAMAPT
SCHEMBL28438497 0.82 HSD17B3 (0.47) ALDH1A1CA12CA9MAPK1CDC25B
Benzamide SCHEMBL28196827 0.82 CYP2C19 (0.52) RAB9AMEN1KMT2ALMNAMAPT
SCHEMBL41940 0.82 BACE1 (0.46) LMNAMAPTALDH1A1CA12CA9
Benzene SCHEMBL29048034 0.82 BACE1 (0.46) LMNAMAPTALDH1A1CA12CA9
Hydrogen Sulfide SCHEMBL28559443 0.80 HSD17B3 (0.46) ALDH1A1CA12CA9MAPK1CDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 638 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240052005-A1 IMPROVED CELL-PENETRATING PEPTIDES AND FUSION PROTEINS ANASTASIS BIOTEC LIMITED (GB) 2024-02-15 US claimed
EP-4263582-A1 IMPROVED CELL-PENETRATING PEPTIDES AND FUSION PROTEINS Anastasis Biotec Limited (GB) 2023-10-25 EP claimed
CN-116068167-A Separation and detection method of extracellular biomacromolecule 厦门福流生物科技有限公司 2023-05-05 CN claimed
WO-2022129926-A1 IMPROVED CELL-PENETRATING PEPTIDES AND FUSION PROTEINS ANASTASIS BIOTEC LIMITED (GB) 2022-06-23 WO claimed
EP-2478049-B1 A POLYMER SUPPORT UNIV CAPE TOWN (ZA) 2015-02-25 EP claimed
EP-2333548-B1 Biological indicator AMERICAN STERILIZER CO (US) 2014-07-30 EP claimed
EP-2701743-A2 ANTIBODIES SELECTIVE FOR PATHOLOGICAL TAU DIMERS AND PREFIBRILLAR PATHOLOGICAL TAU OLIGOMERS AND THEIR USES IN TREATMENT, DIAGNOSIS AND MONITORING OF TAUOPATHIES North Western University (US) 2014-03-05 EP claimed
US-20130183270-A1 Orally Bioavailable Lipid-Based Constructs SDG, INC. (US) 2013-07-18 US claimed
US-8420802-B2 Polymer support UNIVERSITY OF CAPE TOWN (ZA) 2013-04-16 US claimed
WO-2012149365-A2 ANTIBODIES SELECTIVE FOR PATHOLOGICAL TAU DIMERS AND PREFIBRILLAR PATHOLOGICAL TAU OLIGOMERS AND THEIR USES IN TREATMENT, DIAGNOSIS AND MONITORING OF TAUOPATHIES NORTHWESTERN UNIVERSITY (US) 2012-11-01 WO claimed
WO-2011083360-A1 A POLYMER SUPPORT UNIVERSITY OF CAPE TOWN (ZA) 2011-07-14 WO claimed
EP-2333548-A1 Biological indicator American Sterilizer Company (US) 2011-06-15 EP claimed
WO-2010111271-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS SDG, INC. (AN OHIO CORPORATION) (US) 2010-09-30 WO claimed
US-20100151563-A1 Biological indicator AMERICAN STERILIZER COMPANY (US) 2010-06-17 US claimed
US-20100080773-A1 Orally Bioavailable Lipid-Based Constructs SDG, INC. 2010-04-01 US claimed
US-20080199903-A1 Biological indicator STERIS INC. (US) 2008-08-21 US claimed
CN-101189519-A Biological indicator STERIS INC (US) 2008-05-28 CN claimed
EP-1886143-A1 BIOLOGICAL INDICATOR Steris, Inc. (US) 2008-02-13 EP claimed
WO-2007046865-A1 BIOLOGICAL INDICATOR STERIS, INC. (US) 2007-04-26 WO claimed
US-20060269983-A1 Biological indicator AMERICAN STERILIZER COMPANY 2006-11-30 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100080773-A1 Orally Bioavailable Lipid-Based Constructs FABP2, FABP1, LIPC RAB9A 4107/4885MEN1 1477/4885KMT2A 4808/4885
US-20130183270-A1 Orally Bioavailable Lipid-Based Constructs FABP2, FABP1, LIPC RAB9A 4107/4885MEN1 1477/4885KMT2A 4808/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.