Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | SCN4A | P35499 | 9/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | SCN8A | Q9UQD0 | 4/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SCN1A | P35498 | 2/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.46 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3400233 | 0.89 | TSHR (0.54) | TSHRSCN4ASCN8ACYP2D6LMNA | |
| SCHEMBL773062 | 0.81 | TSHR (0.93) | TSHRSCN4AALOX15SCN8ACYP2D6 | |
| SCHEMBL22305220 | 0.80 | TSHR (0.55) | TSHRSCN4ASCN8ACYP2D6LMNA | |
| SCHEMBL6928489 | 0.76 | SCN4A (0.53) | TSHRSCN4ASCN8ACYP2D6LMNA | |
| SCHEMBL3397865 | 0.75 | SCN4A (0.50) | TSHRSCN4ASCN8ACYP2D6LMNA | |
| SCHEMBL3400703 | 0.75 | KMT2A (0.54) | TSHRKCNH2MEN1KMT2A | |
| SCHEMBL10926972 | 0.74 | ALDH1A1 (0.53) | TSHRSCN4ASCN8ACYP2D6LMNA | |
| SCHEMBL9201467 | 0.74 | SCN4A (0.55) | TSHRSCN4ASCN8ACYP2D6LMNA | |
| SCHEMBL3399258 | 0.73 | SCN4A (0.56) | TSHRSCN4ASCN8ACYP2D6LMNA | |
| SCHEMBL3400079 | 0.73 | SCN4A (0.54) | TSHRSCN4ASCN8ACYP2D6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247571-A2 | DERIVATIVES OF AMINOALKANOLS, METHOD OF OBTAINING OF AMINOALKANOLS AND THEIR USE | Uniwersytet Jagiellonski (PL) | 2010-11-10 | — | — | EP | claimed |
| WO-2009093916-A2 | DERIVATIVES OF AMINOALKANOLS, METHOD OF OBTAINING AMINOALKANOLS AND THEIR USE | UNIWERSYTET JAGIELLONSKI (PL) | 2009-07-30 | — | — | WO | claimed |
| CN-106431941-A | DERIVATIVES OF AMINOALKANOLS, METHOD OF OBTAINING OF AMINOALKANOLS AND THEIR USE | 雅盖隆大学 | 2017-02-22 | — | — | CN | disclosed |