Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SCN8A | Q9UQD0 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SCN1A | P35498 | 2/20 | 0.52 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.52 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.52 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.52 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.52 |
| ▸ | GBA1 | P04062 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10926972 | 0.94 | ALDH1A1 (0.53) | SCN4AALDH1A1SCN8ALMNASCN1A | |
| SCHEMBL9201467 | 0.89 | SCN4A (0.55) | SCN4AALDH1A1SCN8ALMNASCN1A | |
| SCHEMBL6373909 | 0.80 | ALDH1A1 (0.55) | SCN4AALDH1A1SCN8ALMNASCN1A | |
| SCHEMBL4382775 | 0.80 | ALDH1A1 (0.55) | SCN4AALDH1A1SCN8ALMNASCN1A | |
| SCHEMBL3400233 | 0.79 | TSHR (0.54) | SCN4AALDH1A1SCN8ALMNASCN1A | |
| SCHEMBL10693012 | 0.79 | HTR1B (0.42) | SCN4AALDH1A1SCN8ALMNASCN1A | |
| SCHEMBL23817559 | 0.78 | ALDH1A1 (0.54) | SCN4AALDH1A1SCN8ALMNASCN1A | |
| SCHEMBL6470644 | 0.78 | ALDH1A1 (0.53) | SCN4AALDH1A1SCN8ALMNASCN1A | |
| SCHEMBL10768133 | 0.78 | ALDH1A1 (0.53) | SCN4AALDH1A1SCN8ALMNASCN1A | |
| SCHEMBL28042959 | 0.78 | ALDH1A1 (0.53) | SCN4AALDH1A1SCN8ALMNASCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1365757-A1 | NEW USE | Isomex Limited (GB) | 2003-12-03 | — | — | EP | claimed |
| WO-2002062328-A1 | NEW USE | ISOMEX LIMITED (GB) | 2002-08-15 | — | — | WO | claimed |
| US-10577308-B2 | Sodium channel modulators | The Florey Institute (AU) | 2020-03-03 | — | — | US | disclosed |
| EP-3297990-A1 | SODIUM CHANNEL MODULATORS | The Florey Institute Of Neuroscience And Mental Health (AU) | 2018-03-28 | — | — | EP | disclosed |
| US-20180072656-A1 | Sodium Channel Modulators | THE UNIVERSITY OF MELBOURNE (AU) | 2018-03-15 | — | — | US | disclosed |
| WO-2016149765-A1 | SODIUM CHANNEL MODULATORS | THE FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH (AU) | 2016-09-29 | — | — | WO | disclosed |
| EP-1365757-A1 | NEW USE | Isomex Limited (GB) | 2003-12-03 | — | — | EP | disclosed |
| WO-2002062328-A1 | NEW USE | ISOMEX LIMITED (GB) | 2002-08-15 | — | — | WO | disclosed |
| EP-0183147-A2 | Beta-substituted aminophenethylazol derivatives | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-06-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180072656-A1 | Sodium Channel Modulators | SCN1B, SCNN1G, SCN2B | SCN4A 13/4885ALDH1A1 1159/4885SCN8A 16/4885 |
| US-10577308-B2 | Sodium channel modulators | SCN1B, SCNN1G, SCN2B | SCN4A 13/4885ALDH1A1 1159/4885SCN8A 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.