Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 9/20 | 0.55 |
| ▸ | SCN8A | Q9UQD0 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SCN1A | P35498 | 2/20 | 0.53 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.53 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.53 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.53 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.53 |
| ▸ | GBA1 | P04062 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6928489 | 0.89 | SCN4A (0.53) | SCN4ASCN8ALMNASCN1ASCN5A | |
| SCHEMBL10926972 | 0.87 | ALDH1A1 (0.53) | SCN4ASCN8ALMNASCN1ASCN5A | |
| SCHEMBL21601403 | 0.86 | KDM4E (0.61) | SCN4ASCN8ALMNASCN1ASCN5A | |
| Hydrochloric Acid SCHEMBL21595745 | 0.85 | KDM4E (0.59) | SCN4ASCN8ALMNASCN1ASCN5A | |
| SCHEMBL29057024 | 0.80 | ALDH1A1 (0.57) | CYP3A4CYP2C9ALDH1A1KDM4ETAAR1 | |
| SCHEMBL1991553 | 0.79 | ALDH1A1 (0.52) | SCN4ASCN8ALMNASCN1ASCN5A | |
| SCHEMBL22305220 | 0.78 | TSHR (0.55) | SCN4ASCN8ALMNASCN1ASCN5A | |
| SCHEMBL15089976 | 0.77 | ALDH1A1 (0.50) | SCN4ASCN8ALMNASCN1ASCN5A | |
| SCHEMBL4382775 | 0.77 | ALDH1A1 (0.55) | SCN4ASCN8ALMNASCN1ASCN5A | |
| Ammonia Solution, Strong SCHEMBL8858388 | 0.77 | ALDH1A1 (0.50) | SCN4ASCN8ALMNASCN1ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019244066-A2 | PYRIDIN-3-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV Healthcare UK (No.5) Limited (GB) | 2019-12-26 | — | — | WO | disclosed |
| WO-2019244066-A2 | PYRIDIN-3-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV Healthcare UK (No.5) Limited (GB) | 2019-12-26 | — | — | WO | disclosed |
| EP-0403703-B1 | Maleimide derivative, process for the preparation thereof, and agricultural and horticultural fungicide containing said maleimide derivative as active ingredient | SUNTORY LTD (JP) | 1995-09-06 | — | — | EP | disclosed |
| EP-0403703-A1 | Maleimide derivative, process for the preparation thereof, and agricultural and horticultural fungicide containing said maleimide derivative as active ingredient | SUNTORY LIMITED (JP) | 1990-12-27 | — | — | EP | disclosed |
| US-4945104-A | Maleimide derivatives and use thereof in agricultural and horticultural fungicides | SUNTORY LIMITED (JP) | 1990-07-31 | — | — | US | disclosed |
| EP-0183147-A2 | Beta-substituted aminophenethylazol derivatives | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-06-04 | — | — | EP | disclosed |