Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | BLVRB | P30043 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 2/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31702340 | 0.85 | KMT2A (0.57) | TRPA1TDP1MAPK1KMT2AMEN1 | |
| SCHEMBL8520930 | 0.83 | CYP3A4 (0.50) | CYP3A4TRPA1TDP1MAPK1KMT2A | |
| SCHEMBL2515790 | 0.82 | TRPA1 (0.46) | CYP3A4TRPA1TDP1MAPK1KMT2A | |
| SCHEMBL9679696 | 0.80 | CYP3A4 (0.55) | CYP3A4TRPA1TDP1MAPK1KMT2A | |
| SCHEMBL12589872 | 0.79 | RXRB (0.45) | TDP1MAPK1KMT2AMEN1PDE4A | |
| SCHEMBL16829602 | 0.79 | CYP3A4 (0.42) | CYP3A4TRPA1TDP1MAPK1KMT2A | |
| SCHEMBL1516761 | 0.79 | CYP3A4 (0.42) | CYP3A4TRPA1TDP1MAPK1KMT2A | |
| SCHEMBL31701516 | 0.79 | TRPA1 (0.58) | TRPA1TDP1MAPK1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL10392668 | 0.79 | CYP3A4 (0.53) | CYP3A4TRPA1TDP1MAPK1KMT2A | |
| SCHEMBL1099682 | 0.78 | ALDH1A1 (0.54) | CYP3A4TRPA1TDP1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2445345-B1 | BENZAMIDE DERIVATIVES | TRANSLATIONAL GENOMICS RES INST (US) | 2014-08-27 | — | — | EP | claimed |
| EP-4713378-A1 | ESTERIFIED ETHANOLAMINES FOR PREPARING ISOCYANURATE POLYMERS | Covestro Deutschland AG (DE) | 2026-03-25 | — | — | EP | disclosed |
| WO-2024236000-A1 | ESTERIFIED ETHANOLAMINES FOR PREPARING ISOCYANURATE POLYMERS | COVESTRO DEUTSCHLAND AG (DE) | 2024-11-21 | — | — | WO | disclosed |
| EP-4464727-A1 | ESTERIFIED ETHANOLAMINES FOR THE PREPARATION OF ISOCYANURATE POLYMERS | Covestro Deutschland AG (DE) | 2024-11-20 | — | — | EP | disclosed |
| US-11873432-B2 | Luminescent materials including a luminescent benzothiazole, articles including a security feature, and methods of forming luminescent particles including a luminescent benzothiazole | HONEYWELL INTERNATIONAL INC. (US) | 2024-01-16 | — | — | US | disclosed |
| EP-3887477-B1 | LUMINESCENT MATERIALS INCLUDING A LUMINESCENT BENZOTHIAZOLE, ARTICLES INCLUDING A SECURITY FEATURE, AND METHODS OF FORMING LUMINESCENT PARTICLES INCLUDING A LUMINESCENT BENZOTHIAZOLE | HONEYWELL INT INC (US) | 2024-01-03 | — | — | EP | disclosed |
| EP-3481822-B1 | MULTIFUNCTIONAL INHIBITORS OF MEK/PI3K AND MTOR/MEK/PI3K BIOLOGICAL PATHWAYS AND THERAPEUTIC METHODS USING THE SAME | UNIV MICHIGAN REGENTS (US) | 2022-06-22 | — | — | EP | disclosed |
| EP-3997149-A1 | POLYMERIZABLE COMPOSITIONS FOR PREPARING POLYISOCYANURATE-BASED PLASTICS HAVING EXTENDED WORKLIFE | Covestro Intellectual Property GmbH & Co. KG (DE) | 2022-05-18 | — | — | EP | disclosed |
| EP-3887477-A1 | LUMINESCENT MATERIALS INCLUDING A LUMINESCENT BENZOTHIAZOLE, ARTICLES INCLUDING A SECURITY FEATURE, AND METHODS OF FORMING LUMINESCENT PARTICLES INCLUDING A LUMINESCENT BENZOTHIAZOLE | Honeywell International Inc. (US) | 2021-10-06 | — | — | EP | disclosed |
| WO-2021004842-A1 | POLYMERIZABLE COMPOSITIONS FOR PREPARING POLYISOCYANURATE-BASED PLASTICS HAVING EXTENDED WORKLIFE | COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) | 2021-01-14 | — | — | WO | disclosed |
| US-20200172803-A1 | LUMINESCENT MATERIALS INCLUDING A LUMINESCENT BENZOTHIAZOLE, ARTICLES INCLUDING A SECURITY FEATURE, AND METHODS OF FORMING LUMINESCENT PARTICLES INCLUDING A LUMINESCENT BENZOTHIAZOLE | HONEYWELL INTERNATIONAL INC. (US) | 2020-06-04 | — | — | US | disclosed |
| WO-2020113016-A1 | LUMINESCENT MATERIALS INCLUDING A LUMINESCENT BENZOTHIAZOLE, ARTICLES INCLUDING A SECURITY FEATURE, AND METHODS OF FORMING LUMINESCENT PARTICLES INCLUDING A LUMINESCENT BENZOTHIAZOLE | HONEYWELL INTERNATIONAL INC. (US) | 2020-06-04 | — | — | WO | disclosed |
| EP-3481822-A1 | MULTIFUNCTIONAL INHIBITORS OF MEK/PI3K AND mTOR/MEK/PI3K BIOLOGICAL PATHWAYS AND THERAPEUTIC METHODS USING THE SAME | The Regents of The University of Michigan (US) | 2019-05-15 | — | — | EP | disclosed |
| WO-2018009638-A1 | MULTIFUNCTIONAL INHIBITORS OF MEK/PI3K AND mTOR/MEK/PI3K BIOLOGICAL PATHWAYS AND THERAPEUTIC METHODS USING THE SAME | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2018-01-11 | — | — | WO | disclosed |
| WO-2014141035-A2 | FUSED HETEROCYCLYL DERIVATIVES AS NAMPT INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2014-09-18 | — | — | WO | disclosed |
| EP-2252296-A1 | 3H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE COMPOUNDS, THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES | Wyeth LLC (US) | 2010-11-24 | — | — | EP | disclosed |
| WO-2009091788-A1 | 3H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE COMPOUNDS, THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES | WYETH (US) | 2009-07-23 | — | — | WO | disclosed |
| US-20090181963-A1 | 3H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE COMPOUNDS, THEIR USE AS mTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES | WYETH (US) | 2009-07-16 | — | — | US | disclosed |
| US-20050042674-A9 | Common ligand mimics: thiazolidinediones and rhodanines | TRIAD THERAPEUTICS, INC. | 2005-02-24 | — | — | US | disclosed |
| US-20050019825-A9 | Common ligand mimics: pseudothiohydantoins | TRIAD THERAPEUTICS, INC. | 2005-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050019825-A9 | Common ligand mimics: pseudothiohydantoins | FGFR3, BID, FLT3 | CYP3A4 846/4885TRPA1 485/4885TDP1 4871/4885 |
| US-20090181963-A1 | 3H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE COMPOUNDS, THEIR USE AS mTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES | MTOR, PIK3CA, PIK3CD | CYP3A4 1276/4885TRPA1 3216/4885TDP1 918/4885 |
| US-20050042674-A9 | Common ligand mimics: thiazolidinediones and rhodanines | GPR65, NR2E3, FGFR3 | CYP3A4 784/4885TRPA1 264/4885TDP1 4844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.