Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 10/20 | 0.65 |
| ▸ | RAD52 | P43351 | 3/20 | 0.62 |
| ▸ | TP53 | P04637 | 5/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.60 |
| ▸ | HTR1A | P08908 | 4/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.60 |
| ▸ | DRD3 | P35462 | 4/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.60 |
| ▸ | DRD1 | P21728 | 3/20 | 0.60 |
| ▸ | THPO | P40225 | 3/20 | 0.60 |
| ▸ | MTOR | P42345 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4278875 | 0.90 | FPR2 (0.60) | FPR2RAD52TP53MAPK1CYP1A2 | |
| SCHEMBL4283601 | 0.90 | TP53 (0.76) | FPR2RAD52TP53MAPK1CYP1A2 | |
| SCHEMBL4273505 | 0.85 | FPR2 (0.75) | FPR2RAD52TP53MAPK1CYP1A2 | |
| SCHEMBL13346862 | 0.84 | LMNA (0.79) | FPR2RAD52TP53MAPK1CYP1A2 | |
| SCHEMBL4279887 | 0.83 | FPR2 (0.84) | FPR2RAD52TP53MAPK1CYP1A2 | |
| SCHEMBL10168007 | 0.83 | FPR2 (0.72) | FPR2RAD52TP53MAPK1CYP1A2 | |
| SCHEMBL10168005 | 0.83 | FPR2 (0.64) | FPR2RAD52TP53MAPK1CYP1A2 | |
| SCHEMBL4277186 | 0.83 | TP53 (0.65) | FPR2RAD52TP53MAPK1CYP1A2 | |
| SCHEMBL4281060 | 0.83 | FPR2 (0.68) | FPR2RAD52TP53MAPK1CYP1A2 | |
| SCHEMBL4277176 | 0.82 | FPR2 (0.57) | FPR2RAD52TP53MAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247293-A2 | NOVEL COMPOSITIONS AND METHODS FOR TREATMENT OF DISEASES RELATED TO ACTIVATED LYMPHOCYTES | Immune Control, Inc. (US) | 2010-11-10 | — | — | EP | disclosed |
| WO-2009108635-A2 | NOVEL COMPOSITIONS AND METHODS FOR TREATMENT OF DISEASES RELATED TO ACTIVATED LYMPHOCYTES | IMMUNE CONTROL, INC. (US) | 2009-09-03 | — | — | WO | disclosed |