Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.76 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.76 |
| ▸ | HTR1A | P08908 | 3/20 | 0.76 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.76 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.76 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.76 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.76 |
| ▸ | DRD1 | P21728 | 3/20 | 0.76 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.76 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.76 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.76 |
| ▸ | DRD3 | P35462 | 3/20 | 0.76 |
| ▸ | THPO | P40225 | 3/20 | 0.76 |
| ▸ | MTOR | P42345 | 3/20 | 0.76 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.76 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.76 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.76 |
| ▸ | NPC1 | O15118 | 2/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23353457 | 0.90 | TP53 (0.85) | TP53MAPK1CYP1A2ABCB1HTR1A | |
| SCHEMBL3399336 | 0.90 | FPR2 (0.65) | TP53MAPK1CYP1A2ABCB1HTR1A | |
| SCHEMBL4273505 | 0.88 | FPR2 (0.75) | TP53MAPK1CYP1A2ABCB1HTR1A | |
| SCHEMBL4279887 | 0.88 | FPR2 (0.84) | TP53MAPK1CYP1A2ABCB1HTR1A | |
| Trifluoperazine SCHEMBL28057424 | 0.88 | FPR2 (0.86) | TP53MAPK1CYP1A2ABCB1HTR1A | |
| SCHEMBL10168007 | 0.88 | FPR2 (0.72) | TP53MAPK1CYP1A2ABCB1HTR1A | |
| Triflupromazine SCHEMBL32668886 | 0.87 | CYP1A2 (1.00) | TP53MAPK1CYP1A2ABCB1HTR1A | |
| Triflupromazine SCHEMBL44085 | 0.87 | CYP1A2 (1.00) | TP53MAPK1CYP1A2ABCB1HTR1A | |
| SCHEMBL4281060 | 0.87 | FPR2 (0.68) | TP53MAPK1CYP1A2ABCB1HTR1A | |
| SCHEMBL561133 | 0.87 | FPR2 (0.70) | TP53MAPK1CYP1A2ABCB1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130457-A1 | Phenothiazine Derivatives for Treatment of Asthma | IMMUNE CONTROL, INC. | 2010-05-27 | — | — | US | disclosed |
| US-20100130457-A1 | Phenothiazine Derivatives for Treatment of Asthma | IMMUNE CONTROL, INC. | 2010-05-27 | — | — | US | disclosed |
| WO-2010056979-A1 | PHENOTHIAZINE DERIVATIVES FOR TREATMENT OF ASTHMA | IMMUNE CONTROL, INC. (US) | 2010-05-20 | — | — | WO | disclosed |
| US-20100035858-A1 | Novel Compositions and Methods for Binding and Inhibiting 5-HT4 Receptor | IMMUNE CONTROL, INC. | 2010-02-11 | — | — | US | disclosed |
| US-20100035858-A1 | Novel Compositions and Methods for Binding and Inhibiting 5-HT4 Receptor | IMMUNE CONTROL, INC. | 2010-02-11 | — | — | US | disclosed |
| WO-2010009332-A1 | BINDING AND INHIBITING 5-HT4 RECEPTOR | IMMUNE CONTROL, INC. (US) | 2010-01-21 | — | — | WO | disclosed |
| US-20090275557-A1 | Novel Composition for Treatment of Diseases Related to Activated Lymphocytes | IMMUNE CONTROL, INC. (US) | 2009-11-05 | — | — | US | disclosed |
| US-20090275557-A1 | Novel Composition for Treatment of Diseases Related to Activated Lymphocytes | IMMUNE CONTROL, INC. (US) | 2009-11-05 | — | — | US | disclosed |
| US-20090275557-A1 | Novel Composition for Treatment of Diseases Related to Activated Lymphocytes | IMMUNE CONTROL, INC. (US) | 2009-11-05 | — | — | US | disclosed |
| WO-2009108635-A2 | NOVEL COMPOSITIONS AND METHODS FOR TREATMENT OF DISEASES RELATED TO ACTIVATED LYMPHOCYTES | IMMUNE CONTROL, INC. (US) | 2009-09-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130457-A1 | Phenothiazine Derivatives for Treatment of Asthma | IL5, HRH4, TLR5 | TP53 3898/4885MAPK1 3372/4885CYP1A2 132/4885 |
| US-20100035858-A1 | Novel Compositions and Methods for Binding and Inhibiting 5-HT4 Receptor | HTR4, HTR3B, HTR5A | TP53 2701/4885MAPK1 1859/4885CYP1A2 4422/4885 |
| US-20090275557-A1 | Novel Composition for Treatment of Diseases Related to Activated Lymphocytes | TPH1, HTR5A, HTR6 | TP53 1694/4885MAPK1 1697/4885CYP1A2 2446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.