SCHEMBL3399609

SCHEMBL3399609

CCCCCC[SiH2]CCCC

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.53
THRB P10828 1/20 0.53
DNM1 Q05193 9/20 0.47
ALDH1A1 P00352 3/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
EPHX1 P07099 1/20 0.47
LMNA P02545 2/20 0.40
HSD17B10 Q99714 1/20 0.40
SLC22A1 O15245 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10841573 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1MEN1
Water SCHEMBL28337790 0.97 TSHR (0.50) TSHRTHRBDNM1ALDH1A1MEN1
SCHEMBL2511627 0.97 TSHR (0.57) TSHRTHRBDNM1ALDH1A1MEN1
SCHEMBL16209849 0.97 TSHR (0.57) TSHRTHRBDNM1ALDH1A1MEN1
SCHEMBL17386447 0.97 TSHR (0.57) TSHRTHRBDNM1ALDH1A1MEN1
SCHEMBL10803622 0.97 TSHR (0.57) TSHRTHRBDNM1ALDH1A1MEN1
SCHEMBL2512253 0.97 TSHR (0.57) TSHRTHRBDNM1ALDH1A1MEN1
SCHEMBL17386495 0.97 TSHR (0.57) TSHRTHRBDNM1ALDH1A1MEN1
SCHEMBL181208 0.97 TSHR (0.57) TSHRTHRBDNM1ALDH1A1MEN1
SCHEMBL10841351 0.97 TSHR (0.57) TSHRTHRBDNM1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1828266-A1 METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS Novolen Technology Holdings, C.V. (NL) 2007-09-05 EP claimed
US-7169864-B2 Loeading and heating a catalyst support with an alumoxane and further loading with a Group IVB metallocene and a second aluminoxane cocatalyst alone or in combination with a Lewis Acid or ionic compound; improved catalyst selectivity and polymerization efficiency NOVOLEN TECHNOLOGY HOLDINGS, C.V. (NL) 2007-01-30 US claimed
WO-2006060544-A1 METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) 2006-06-08 WO claimed
US-20060116490-A1 Metallocene catalysts, their synthesis and their use for the polymerization of olefins LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) 2006-06-01 US claimed
EP-3915995-B1 PROCESS FOR THE STEPWISE SYNTHESIS OF SILAHYDROCARBONS MOMENTIVE PERFORMANCE MAT INC (US) 2025-11-26 EP disclosed
US-20230192731-A1 PROCESS FOR THE STEPWISE SYNTHESIS OF SILAHYDROCARBONS MOMENTIVE PERFORMANCE MATERIALS INC. 2023-06-22 US disclosed
EP-1828266-B1 SUPPORTED METALLOCENE CATALYST COMPOSITIONS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) 2015-07-22 EP disclosed
WO-2013041619-A1 PROCESS FOR RECYCLING OF FREE LIGAND FROM THEIR CORRESPONDING METALLOCENE COMPLEXES LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) 2013-03-28 WO disclosed
EP-2573091-A1 PROCESS FOR RECYCLING OF FREE LIGAND FROM THEIR CORRESPONDING METALLOCENE COMPLEXES Lummus Novolen Technology Gmbh (DE) 2013-03-27 EP disclosed
EP-1882000-B1 CATALYST COMPOSITION FOR OLEFIN POLYMERIZATION NOVOLEN TECH HOLDINGS CV (NL) 2010-03-31 EP disclosed
US-7468416-B2 Catalyst composition for olefin polymerization LUMMUS TECHNOLOGY INC. (US) 2008-12-23 US disclosed
US-20080287286-A1 Metallocene catalysts, their synthesis and their use for the polymerization of olefins PACZKOWSKI NICOLA S 2008-11-20 US disclosed
EP-1828266-A1 METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS Novolen Technology Holdings, C.V. (NL) 2007-09-05 EP disclosed
US-7232869-B2 Catalyst composition for olefin polymerization NOVOLEN TECHNOLOGY HOLDINGS, C.V. (NL) 2007-06-19 US disclosed
US-20070082806-A1 Metallocene catalysts, their synthesis and their use for the polymerization of olefins PACZKOWSKI NICOLA S 2007-04-12 US disclosed
US-7169864-B2 Loeading and heating a catalyst support with an alumoxane and further loading with a Group IVB metallocene and a second aluminoxane cocatalyst alone or in combination with a Lewis Acid or ionic compound; improved catalyst selectivity and polymerization efficiency NOVOLEN TECHNOLOGY HOLDINGS, C.V. (NL) 2007-01-30 US disclosed
WO-2006124231-A1 CATALYST COMPOSITION FOR OLEFIN POLYMERIZATION NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) 2006-11-23 WO disclosed
US-20060264587-A1 Catalyst composition for olefin polymerization NOVOLEN TECHNOLOGY HOLDINGS, C.V. (NL) 2006-11-23 US disclosed
WO-2006060544-A1 METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) 2006-06-08 WO disclosed
US-20060116490-A1 Metallocene catalysts, their synthesis and their use for the polymerization of olefins LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) 2006-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192731-A1 PROCESS FOR THE STEPWISE SYNTHESIS OF SILAHYDROCARBONS CCR4, SALL4, CCR2 TSHR 4142/4885THRB 4192/4885DNM1 4086/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.