Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.62 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.54 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.54 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3399511 | 0.95 | SIGMAR1 (0.62) | SIGMAR1L3MBTL1 | |
| SCHEMBL3399836 | 0.87 | GAA (0.57) | SIGMAR1L3MBTL1 | |
| SCHEMBL6033711 | 0.86 | SIGMAR1 (0.66) | SIGMAR1LMNATSHRS1PR2S1PR4 | |
| SCHEMBL11330006 | 0.84 | SIGMAR1 (0.69) | SIGMAR1TRPV1LMNATSHRS1PR2 | |
| Hydrochloric Acid SCHEMBL5695091 | 0.84 | SIGMAR1 (0.63) | SIGMAR1LMNATSHRS1PR2S1PR4 | |
| SCHEMBL4953206 | 0.83 | SIGMAR1 (0.61) | SIGMAR1TRPV1S1PR2S1PR4S1PR1 | |
| SCHEMBL425222 | 0.82 | TRPV1 (0.65) | TRPV1LMNATSHRASAH1L3MBTL1 | |
| SCHEMBL158734 | 0.80 | SIGMAR1 (0.67) | SIGMAR1S1PR1S1PR3L3MBTL1 | |
| SCHEMBL5695106 | 0.80 | SIGMAR1 (0.58) | SIGMAR1TRPV1S1PR2S1PR4S1PR1 | |
| SCHEMBL23033613 | 0.80 | SIGMAR1 (0.73) | SIGMAR1S1PR2S1PR4S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015703-A2 | NOVEL 6-O-SUBSTITUTED 15-MEMBERED 8A- AND 9A-LACTAMS | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. (HR) | 2010-02-11 | — | — | WO | disclosed |