Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.47 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3399511 | 0.89 | SIGMAR1 (0.62) | GAAKDM4ESIGMAR1TAAR1KMT2A | |
| SCHEMBL3399795 | 0.87 | SIGMAR1 (0.62) | SIGMAR1L3MBTL1 | |
| SCHEMBL157742 | 0.84 | KEAP1 (0.59) | GAAMAPTALDH1A1KDM4ESIGMAR1 | |
| Hydrochloric Acid SCHEMBL10493762 | 0.82 | MAPT (0.59) | GAAMAPTALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL27759805 | 0.82 | KEAP1 (0.57) | GAAMAPTALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL4344215 | 0.81 | TAAR1 (0.54) | GAAMAPTALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL8360505 | 0.81 | ALDH1A1 (0.57) | GAAMAPTALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL18739762 | 0.80 | SIGMAR1 (0.55) | GAAMAPTALDH1A1SIGMAR1TAAR1 | |
| Bicarbonate SCHEMBL11575509 | 0.80 | GAA (0.80) | GAAMAPTALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL3394144 | 0.80 | CYP1A2 (0.51) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015703-A2 | NOVEL 6-O-SUBSTITUTED 15-MEMBERED 8A- AND 9A-LACTAMS | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. (HR) | 2010-02-11 | — | — | WO | disclosed |