Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3399795 | 0.95 | SIGMAR1 (0.62) | SIGMAR1L3MBTL1 | |
| SCHEMBL3399836 | 0.89 | GAA (0.57) | SIGMAR1L3MBTL1GAATAAR1KDM4E | |
| SCHEMBL158734 | 0.85 | SIGMAR1 (0.67) | SIGMAR1L3MBTL1NPC1RAB9AGAA | |
| SCHEMBL4948686 | 0.82 | SIGMAR1 (0.62) | SIGMAR1L3MBTL1NPC1RAB9AGAA | |
| SCHEMBL422826 | 0.81 | L3MBTL1 (0.68) | L3MBTL1NPC1RAB9AGAAHPGD | |
| SCHEMBL11482367 | 0.81 | NPC1 (0.61) | SIGMAR1L3MBTL1NPC1RAB9AGAA | |
| SCHEMBL6033711 | 0.80 | SIGMAR1 (0.66) | SIGMAR1 | |
| SCHEMBL29204655 | 0.80 | SIGMAR1 (0.64) | SIGMAR1KMT2A | |
| SCHEMBL9543983 | 0.79 | SIGMAR1 (0.58) | SIGMAR1L3MBTL1NPC1RAB9AGAA | |
| SCHEMBL6263723 | 0.79 | SIGMAR1 (0.75) | SIGMAR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015703-A2 | NOVEL 6-O-SUBSTITUTED 15-MEMBERED 8A- AND 9A-LACTAMS | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. (HR) | 2010-02-11 | — | — | WO | disclosed |