Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 4/20 | 1.00 |
| ▸ | HTR5A | P47898 | 4/20 | 1.00 |
| ▸ | HTR2C | P28335 | 2/20 | 1.00 |
| ▸ | BCHE | P06276 | 2/20 | 0.65 |
| ▸ | TDO2 | P48775 | 11/20 | 0.63 |
| ▸ | IDO1 | P14902 | 4/20 | 0.58 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.58 |
| ▸ | CDK1 | P06493 | 1/20 | 0.58 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.58 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.58 |
| ▸ | CDK2 | P24941 | 1/20 | 0.58 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.58 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.58 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.58 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.58 |
| ▸ | PIM1 | P11309 | 1/20 | 0.56 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | GABRP | O00591 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29959679 | 1.00 | HTR2B (1.00) | HTR2BHTR5AHTR2CBCHETDO2 | |
| SCHEMBL27817460 | 0.84 | TDO2 (0.80) | HTR2BHTR5AHTR2CBCHETDO2 | |
| SCHEMBL29130512 | 0.80 | BCHE (0.71) | HTR2BHTR5AHTR2CBCHETDO2 | |
| SCHEMBL13003646 | 0.79 | HTR2B (0.64) | HTR2BHTR5AHTR2CBCHETDO2 | |
| SCHEMBL29130522 | 0.79 | BCHE (0.69) | HTR2BHTR5AHTR2CBCHETDO2 | |
| SCHEMBL28811802 | 0.79 | BCHE (0.69) | HTR2BHTR5AHTR2CBCHETDO2 | |
| SCHEMBL17102943 | 0.79 | BCHE (0.69) | HTR2BHTR5AHTR2CBCHETDO2 | |
| SCHEMBL24105915 | 0.78 | TDO2 (1.00) | HTR2BHTR5AHTR2CBCHETDO2 | |
| SCHEMBL30431392 | 0.78 | TDO2 (1.00) | HTR2BHTR5AHTR2CBCHETDO2 | |
| SCHEMBL8704484 | 0.76 | HTR2C (0.61) | HTR2BHTR5AHTR2CBCHETDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115093410-B | Preparation method of beta-carboline compound | 南京工业大学 | 2023-09-26 | — | — | CN | disclosed |
| CN-115093410-A | Preparation method of beta-carboline compound | 南京工业大学 | 2022-09-23 | — | — | CN | disclosed |
| US-20120283282-A1 | Photoproducts of Tryptophan, Their Synthesis and Uses Thereof | RIFKIND ARLEEN (US) | 2012-11-08 | — | — | US | disclosed |
| US-20120283282-A1 | Photoproducts of Tryptophan, Their Synthesis and Uses Thereof | RIFKIND ARLEEN (US) | 2012-11-08 | — | — | US | disclosed |
| US-20120283282-A1 | Photoproducts of Tryptophan, Their Synthesis and Uses Thereof | RIFKIND ARLEEN (US) | 2012-11-08 | — | — | US | disclosed |
| WO-2010148350-A1 | PHOTOPRODUCTS OF TRYPTOPHAN, THEIR SYNTHESIS AND USES THEREOF | CORNELL UNIVERSITY (US) | 2010-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283282-A1 | Photoproducts of Tryptophan, Their Synthesis and Uses Thereof | AHR, ARNT, TPH1 | HTR2B 152/4885HTR5A 113/4885HTR2C 89/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.