Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 5/20 | 0.42 |
| ▸ | MAOB | P27338 | 5/20 | 0.42 |
| ▸ | TDO2 | P48775 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | CHUK | O15111 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | TOP1 | P11387 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17861173 | 0.86 | ATM (0.45) | IMPDH2KDM4EALDH1A1 | |
| SCHEMBL22461750 | 0.76 | MAOA (0.46) | MAOAMAOBTDO2KDM4EGABRP | |
| SCHEMBL12383068 | 0.75 | MAOA (0.41) | MAOAMAOBTDO2KDM4EGABRP | |
| SCHEMBL31321551 | 0.74 | MAOA (0.40) | MAOAMAOBTDO2KDM4EGABRP | |
| SCHEMBL5021391 | 0.73 | KDM4E (0.50) | MAOAMAOBTDO2KDM4EGABRP | |
| SCHEMBL16356754 | 0.73 | KDM4E (0.50) | MAOAMAOBTDO2KDM4EGABRP | |
| SCHEMBL15428469 | 0.73 | KDM4E (0.67) | MAOAMAOBKDM4EALDH1A1IDO1 | |
| SCHEMBL30322705 | 0.72 | IDO1 (0.44) | MAPK1MAOAMAOBTDO2KDM4E | |
| SCHEMBL7375006 | 0.71 | TDO2 (0.45) | IMPDH2MAPK1HSD17B10TDO2PIM1 | |
| SCHEMBL18252170 | 0.71 | DUSP3 (0.40) | MAPK1MAOAMAOBTDO2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010148350-A1 | PHOTOPRODUCTS OF TRYPTOPHAN, THEIR SYNTHESIS AND USES THEREOF | CORNELL UNIVERSITY (US) | 2010-12-23 | — | — | WO | disclosed |