SCHEMBL340067

SCHEMBL340067

CCCc1ccc(-c2ccc(CCC)cc2O)c(O)c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.72
CNR2 P34972 1/20 0.72
ALOX5 P09917 3/20 0.55
TSHR P16473 2/20 0.50
NFKB1 P19838 2/20 0.50
HIF1A Q16665 2/20 0.50
HSD17B10 Q99714 2/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
DRD2 P14416 1/20 0.50
DRD1 P21728 1/20 0.50
DRD4 P21917 1/20 0.50
DRD5 P21918 1/20 0.50
ADRA1D P25100 1/20 0.50
ADRA1A P35348 1/20 0.50
ADRA1B P35368 1/20 0.50
DRD3 P35462 1/20 0.50
IAPP P10997 3/20 0.48
KDM4E B2RXH2 2/20 0.48
PMP22 Q01453 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL340409 0.86 NPC1 (0.67) CNR1CNR2NFKB1HIF1AHSD17B10
SCHEMBL30309851 0.86 CNR1 (0.72) CNR1CNR2ALOX5TSHRNFKB1
SCHEMBL57143 0.86 CNR1 (0.72) CNR1CNR2ALOX5TSHRNFKB1
SCHEMBL340040 0.85 PPARA (0.62) CNR1CNR2HIF1AHSD17B10CYP3A4
SCHEMBL28581448 0.84 CNR1 (0.58) CNR1CNR2ALOX5HSD17B10HPGD
SCHEMBL19568031 0.84 CNR1 (0.58) CNR1CNR2ALOX5TSHRNFKB1
Ammonia Solution, Strong SCHEMBL8625427 0.84 CNR1 (0.69) CNR1CNR2ALOX5TSHRNFKB1
SCHEMBL662610 0.84 CNR1 (1.00) CNR1CNR2ALOX5TSHRNFKB1
SCHEMBL29380189 0.84 CNR1 (1.00) CNR1CNR2ALOX5TSHRNFKB1
SCHEMBL340476 0.83 PPARA (0.65) HIF1AHSD17B10CYP3A4KDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9315435-B2 Method for producing hydroxyphenylcyclohexanol compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-04-19 US disclosed
US-20150141707-A1 METHOD FOR PRODUCING HYDROXYPHENYLCYCLOHEXANOL COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-05-21 US disclosed
EP-2842930-A1 METHOD FOR PRODUCING HYDROXYPHENYLCYCLOHEXANOL COMPOUND Sumitomo Chemical Company Limited (JP) 2015-03-04 EP disclosed
EP-2271651-B1 ISOTHERMAL PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS DOW GLOBAL TECHNOLOGIES LLC (US) 2014-01-01 EP disclosed
EP-2346887-B1 SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES DOW TECHNOLOGY INVESTMENTS LLC (US) 2013-12-25 EP disclosed
US-8546600-B2 Slurry process for synthesis of bisphosphites and situ use thereof for producing bisphosphite DOW TECHNOLOGY INVESTMENTS LLC 2013-10-01 US disclosed
EP-2257560-B1 SLURRY PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS UNION CARBIDE CHEM PLASTIC (US) 2013-07-17 EP disclosed
US-8471066-B2 Slurry process for phosphoromonochloridite synthesis UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY LLC 2013-06-25 US disclosed
US-8097749-B2 Isothermal process for phosphoromonochloridite synthesis Union Carbide Chemical and Plastics Technology Technology 2012-01-17 US disclosed
US-20110196166-A1 SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES AND SITU USE THEREOF FOR PRODUCING BISPHOSPHITE DOW TECHNOLOGY INVESTMENTS LLC 2011-08-11 US disclosed
US-4284549-A COMPRISING A POLYESTER OF AN AROMATIC DICARBOXYLIC ACID AND A BISPHENOL AN POLYPHENYLENE SULFIDE HOOKER CHEMICALS & PLASTICS CORP. (US) 1981-08-18 US disclosed
US-4256625-A PERFLUOROALKENYLOXY, N-PHOSPHATOALKYL-SULFAMOYL-BENZENE SURFACTANT HOOKER CHEMICALS & PLASTICS CORP. (US) 1981-03-17 US disclosed
US-4251429-A COMPRISING POLYPHENYLENE SULFIDE AND AN AROMATIC POLYESTER HOOKER CHEMICALS & PLASTICS CORP. (US) 1981-02-17 US disclosed
US-4221694-A AROMATIC POLYESTER FROM A BISPHENOL HOOKER CHEMICALS & PLASTICS CORP. (US) 1980-09-09 US disclosed
US-4211687-A AROMATIC POLYESTER, POLYPHENYLENE SULFIDE, HALO DIELS-ADER ADDUCT HOOKER CHEMICALS & PLASTICS CORP. (US) 1980-07-08 US disclosed
EP-0012505-A1 Glass fiber-filled polybutylene terephthalate compositions and molded articles of diminished warpage formed therefrom OCCIDENTAL CHEMICAL CORPORATION (US) 1980-06-25 EP disclosed
US-4187259-A Polymer blends with improved hydrolytic stability comprising a linear aromatic polyester and a methacrylate cross-linked acrylate copolymer HOOKER CHEMICALS & PLASTICS CORP. (US) 1980-02-05 US disclosed
EP-0007171-A1 Polymer compositions, molded articles and films with improved hydrolytic stability HOOKER CHEMICALS & PLASTICS CORP. (US) 1980-01-23 EP disclosed
US-4137278-A TRANSESTERIFICATION CATALYST HOOKER CHEMICALS & PLASTICS CORP. (US) 1979-01-30 US disclosed
US-4126602-A THERMOPLASTIC, MOLDING, HYDROLYTIC STABILITY HOOKER CHEMICALS & PLASTICS CORP. (US) 1978-11-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150141707-A1 METHOD FOR PRODUCING HYDROXYPHENYLCYCLOHEXANOL COMPOUND HSD11B2, CYP21A2, CYP11B2 CNR1 292/4885CNR2 176/4885ALOX5 2196/4885
US-20110196166-A1 SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES AND SITU USE THEREOF FOR PRODUCING BISPHOSPHITE SOST, PLCB3, PPIP5K2 CNR1 1731/4885CNR2 1321/4885ALOX5 787/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.