Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL929248 | 0.81 | ESR1 (0.33) | TSHR | |
| SCHEMBL26048812 | 0.77 | HDAC4 (0.50) | HDAC4HDAC2HDAC8TSHR | |
| SCHEMBL8767509 | 0.77 | TAAR1 (0.45) | — | |
| SCHEMBL21984797 | 0.73 | HDAC4 (0.36) | HDAC4HDAC2HDAC8TSHR | |
| SCHEMBL3115675 | 0.71 | HDAC4 (0.42) | HDAC4HDAC2HDAC8TSHR | |
| SCHEMBL926946 | 0.71 | TSHR (0.37) | TSHR | |
| SCHEMBL9506520 | 0.70 | TSHR (0.40) | TSHR | |
| SCHEMBL3337272 | 0.70 | TSHR (0.33) | TSHR | |
| SCHEMBL18733842 | 0.69 | HDAC4 (0.45) | HDAC4HDAC2HDAC8TSHR | |
| SCHEMBL27999918 | 0.69 | TSHR (0.39) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121349-B1 | RUBBER COMPOSITION, PROCESS OF PREPARING SAME AND ARTICLES MADE THEREFROM | MOMENTIVE PERFORMANCE MAT INC (US) | 2010-11-17 | — | — | EP | disclosed |
| US-7625965-B2 | Rubber composition, process of preparing same and articles made therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2009-12-01 | — | — | US | disclosed |
| EP-2121349-A1 | RUBBER COMPOSITION, PROCESS OF PREPARING SAME AND ARTICLES MADE THEREFROM | Momentive Performance Materials Inc. (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008097587-A1 | RUBBER COMPOSITION, PROCESS OF PREPARING SAME AND ARTICLES MADE THEREFROM | MOMENTIVE PERFORMANCE MATERIALS INC (US) | 2008-08-14 | — | — | WO | disclosed |
| US-20080194746-A1 | Rubber composition, process of preparing same and articles made therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. | 2008-08-14 | — | — | US | disclosed |