Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PGK1 | P00558 | 3/20 | 0.40 |
| ▸ | PGK2 | P07205 | 3/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3115675 | 0.85 | HDAC4 (0.42) | TSHRPGK1PGK2PNMTTAAR1 | |
| SCHEMBL27746360 | 0.83 | PTGS2 (0.42) | TSHRPGK1PGK2PNMTTAAR1 | |
| SCHEMBL7933482 | 0.83 | TSHR (0.44) | TSHRPGK1PGK2PNMTTTR | |
| SCHEMBL27999918 | 0.82 | TSHR (0.39) | TSHRPGK1PGK2PNMTTAAR1 | |
| SCHEMBL26100257 | 0.82 | PNMT (0.44) | TSHRPNMTTAAR1SLC6A2SIGMAR1 | |
| SCHEMBL26100259 | 0.82 | PNMT (0.44) | TSHRPNMTTAAR1SLC6A2SIGMAR1 | |
| (Chloromethyl)Benzene SCHEMBL28389405 | 0.81 | TSHR (0.42) | TSHRTAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL18839099 | 0.81 | DAO (0.45) | TSHRPGK1PGK2PNMT | |
| SCHEMBL26048812 | 0.80 | HDAC4 (0.50) | TSHRPGK1PGK2PNMTTAAR1 | |
| SCHEMBL8897762 | 0.79 | PGK1 (0.44) | TSHRPGK1PGK2TAAR1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0311387-B1 | AROMATIC AMINE RESINS, THEIR PRODUCTION PROCESS AND THERMOSETTING RESIN COMPOSITIONS MAKING USE OF THE SAME | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-08-11 | — | — | EP | disclosed |
| US-5145949-A | Production process for making aromatic amine resins | MITSUI TOATSU CHEMICALS, INC. (JP) | 1992-09-08 | — | — | US | disclosed |
| US-5106953-A | Reacting aromatic amines with bishalogenomethyl derivatives; curing agents or raw materials for polyamides | MITSUI TOATSU CHEMICALS, INC. (JP) | 1992-04-21 | — | — | US | disclosed |
| US-5051494-A | A bismaleimide and an amino resin | MITSUI TOATSU CHEMICALS, INC. (JP) | 1991-09-24 | — | — | US | disclosed |
| US-4937318-A | Aromatic amine resins | MITSUI TOATSU CHEMICALS, INC. (JP) | 1990-06-26 | — | — | US | disclosed |
| US-4260826-A | PHOSPHONIUM CATIONIC SURFACTANTS | THE DOW CHEMICAL COMPANY (US) | 1981-04-07 | — | — | US | disclosed |
| US-4240982-A | CONTAINING ETHER OR POLYETHER COMPONENT | THE DOW CHEMICAL COMPANY (US) | 1980-12-23 | — | — | US | disclosed |
| US-4175196-A | Certain pyridinium surfactants | THE DOW CHEMICAL COMPANY (US) | 1979-11-20 | — | — | US | disclosed |
| US-4093663-A | Novel onium surfactants | THE DOW CHEMICAL COMPANY (US) | 1978-06-06 | — | — | US | disclosed |