SCHEMBL8767509

SCHEMBL8767509

CCO[SiH](CC(C)c1ccccc1)OCC

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.45
AOC3 Q16853 2/20 0.41
TRPA1 O75762 6/20 0.41
RIPK1 Q13546 1/20 0.40
LMNA P02545 1/20 0.36
LTB4R Q15722 1/20 0.36
LTB4R2 Q9NPC1 1/20 0.36
POLB P06746 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9230452 0.80 TAAR1 (0.48) TAAR1AOC3TRPA1RIPK1ALDH1A1
SCHEMBL3360002 0.79 SCN4A (0.43)
SCHEMBL6743964 0.79 LMNA (0.35) TAAR1TRPA1LMNAPOLB
SCHEMBL9716565 0.79 LMNA (0.39) TAAR1TRPA1LMNAPOLB
SCHEMBL929248 0.79 ESR1 (0.33)
SCHEMBL18389692 0.78 TAAR1 (0.47) TAAR1AOC3TRPA1RIPK1ALDH1A1
SCHEMBL3400927 0.77 HDAC4 (0.32)
SCHEMBL3340550 0.74 SIGMAR1 (0.42) TAAR1TRPA1
SCHEMBL3154262 0.74 KCNA5 (0.41) LMNAALDH1A1
SCHEMBL115878 0.74 TAAR1 (0.40) TAAR1AOC3TRPA1LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0385765-A2 Process for polymerizing olefins and catalyst for polymerizing olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1990-09-05 EP claimed
CN-115485624-A Composition for forming resist underlayer film 日产化学株式会社 2022-12-16 CN disclosed
CN-114055975-A Ink jet recording method and ink jet recording apparatus 精工爱普生株式会社 2022-02-18 CN disclosed
EP-0652246-B1 Base-catalysed preparation of an hydrogen containing polyorganosiloxane WACKER CHEMIE GMBH (DE) 1997-08-20 EP disclosed
EP-0652246-A1 Base-catalysed preparation of an hydrogen containing polyorganosiloxane Wacker-Chemie GmbH (DE) 1995-05-10 EP disclosed
EP-0282341-B1 PROCESS FOR POLYMERIZATION OF OLEFINS AND POLYMERIZATION CATALYST MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-05-20 EP disclosed
EP-0455313-A1 Process for polymerization of olefins and polymerization catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-11-06 EP disclosed
US-5028671-A Using coordination catalyst contining magnesium, titanium, halogen compounds with organoaluminum and organosilicon compounds MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-07-02 US disclosed
EP-0282341-A1 Process for polymerization of olefins and polymerization catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-09-14 EP disclosed