Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29253940 | 0.93 | USP2 (0.33) | LMNAUSP2ALDH1A1CYP1A2TSHR | |
| SCHEMBL14690356 | 0.89 | — | — | |
| SCHEMBL11177567 | 0.84 | LMNA (0.33) | LMNAUSP2ALDH1A1CYP1A2TSHR | |
| SCHEMBL28827950 | 0.83 | CPB2 (0.35) | LMNAUSP2ALDH1A1CYP1A2TSHR | |
| SCHEMBL12989448 | 0.83 | LMNA (0.32) | LMNAUSP2ALDH1A1CYP1A2TSHR | |
| SCHEMBL15174049 | 0.83 | USP2 (0.45) | LMNAUSP2ALDH1A1CYP1A2TSHR | |
| SCHEMBL197847 | 0.81 | ALDH1A1 (0.39) | LMNAUSP2ALDH1A1CYP1A2TSHR | |
| SCHEMBL28563379 | 0.81 | USP2 (0.39) | LMNAUSP2ALDH1A1CYP1A2TSHR | |
| SCHEMBL16914222 | 0.80 | — | — | |
| SCHEMBL11753480 | 0.79 | CYP4F2 (0.33) | LMNAUSP2ALDH1A1CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109789142-B | Synthesis of N- (heteroaryl) -pyrrolo [3,2-D ] pyrimidin-2-amines | G1治疗公司 | 2022-08-23 | — | — | CN | disclosed |
| CN-112839657-A | Improved synthesis of 1, 4-diazaspiro [5.5] undecan-3-ones | G1治疗公司 | 2021-05-25 | — | — | CN | disclosed |
| EP-2247588-A2 | FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2010-11-10 | — | — | EP | disclosed |
| WO-2009107850-A2 | FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-09-03 | — | — | WO | disclosed |