Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MELK | Q14680 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | POLQ | O75417 | 1/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL314680 | 1.00 | MELK (0.32) | MELKPDE10ACHRNA7PIK3CDKDM4E | |
| SCHEMBL1972967 | 0.93 | NOS1 (0.31) | — | |
| SCHEMBL1972962 | 0.93 | NOS1 (0.31) | — | |
| SCHEMBL2140499 | 0.90 | ALDH1A1 (0.40) | PDE10ACHRNA7KDM4EALDH1A1HPGD | |
| SCHEMBL2140497 | 0.90 | ALDH1A1 (0.40) | PDE10ACHRNA7KDM4EALDH1A1HPGD | |
| SCHEMBL3399328 | 0.87 | CHRNA7 (0.35) | PDE10ACHRNA7PIK3CDMTORNAAA | |
| SCHEMBL314941 | 0.87 | CHRNA7 (0.35) | PDE10ACHRNA7PIK3CDMTORNAAA | |
| SCHEMBL315460 | 0.86 | CHRNA7 (0.32) | CHRNA7 | |
| SCHEMBL3398167 | 0.86 | NAAA (0.33) | PDE10ACHRNA7PIK3CDNAAA | |
| SCHEMBL315023 | 0.86 | NAAA (0.33) | PDE10ACHRNA7PIK3CDNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066683-B1 | DERIVATIVES OF 5-THIOXYLOPYRANOSE AND USE OF SAME FOR TREATMENT | FOURNIER LAB SA (FR) | 2010-11-03 | — | — | EP | disclosed |