Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 5/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3398468 | 0.94 | MTOR (0.40) | KCNMA1POLBKDM4EALDH1A1MTOR | |
| SCHEMBL3425658 | 0.90 | KCNMA1 (0.40) | KCNMA1MAPTMEN1KMT2APOLB | |
| SCHEMBL2066338 | 0.88 | KCNMA1 (0.46) | KCNMA1MAPTMEN1KMT2APOLB | |
| SCHEMBL3663942 | 0.85 | KCNMA1 (0.44) | KCNMA1MAPTPOLBALDH1A1DRD2 | |
| SCHEMBL3397799 | 0.85 | GSK3B (0.44) | MTOR | |
| SCHEMBL927355 | 0.83 | GSK3B (0.39) | MTOR | |
| SCHEMBL2066032 | 0.83 | F10 (0.45) | KCNMA1MAPTALOX15 | |
| SCHEMBL3402354 | 0.83 | RAB9A (0.36) | MAPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL3660413 | 0.82 | KCNMA1 (0.41) | KCNMA1MAPTPOLBALDH1A1DRD2 | |
| SCHEMBL3668510 | 0.82 | DRD4 (0.45) | KCNMA1MAPTPOLBDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247599-A1 | SUBSTITUTED ARYLAMIDE OXAZEPINOPYRIMIDONE DERIVATIVES | Sanofi-Aventis (FR) | 2010-11-10 | — | — | EP | disclosed |
| WO-2009095788-A1 | SUBSTITUTED ARYLAMIDE OXAZEPINOPYRIMIDONE DERIVATIVES | SANOFI-AVENTIS (FR) | 2009-08-06 | — | — | WO | disclosed |