Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR3 | P25089 | 3/20 | 0.34 |
| ▸ | FPR2 | P25090 | 3/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | CKS1B | P61024 | 1/20 | 0.32 |
| ▸ | SKP1 | P63208 | 1/20 | 0.32 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 2/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | ACACA | Q13085 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2290030 | 0.82 | HDAC3 (0.46) | ATG4BCKS1BSKP1SKP2NAMPT | |
| SCHEMBL3408629 | 0.81 | NAMPT (0.38) | NAMPT | |
| SCHEMBL3406865 | 0.78 | LMNA (0.38) | ACACBACACADRD2 | |
| SCHEMBL3407347 | 0.76 | SCD (0.47) | — | |
| SCHEMBL2290239 | 0.68 | HDAC2 (0.41) | HDAC3HDAC4HDAC6 | |
| SCHEMBL2297207 | 0.66 | OGA (0.48) | HDAC3HDAC4HDAC6ALDH1A1 | |
| SCHEMBL2290893 | 0.64 | NAMPT (0.53) | NAMPTHDAC3HDAC4HDAC6 | |
| SCHEMBL2294470 | 0.62 | CHRM4 (0.45) | HDAC6EGLN1 | |
| SCHEMBL2292781 | 0.61 | SNCA (0.39) | CKS1BSKP1SKP2HDAC3HDAC4 | |
| SCHEMBL4035553 | 0.61 | HDAC2 (0.40) | HDAC3HDAC4HDAC6DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152711-B1 | 2 -HETEROARYL- PYRROLO [3, 4-C]PYRROLE DERIVATIVES AND THEIR USE AS SCD INHIBITORS | SANOFI AVENTIS (FR) | 2010-11-24 | — | — | EP | disclosed |