Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CASP1 | P29466 | 1/20 | 0.62 |
| ▸ | CASP7 | P55210 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1705540 | 0.97 | ALDH1A1 (0.66) | ALDH1A1CYP2C19CYP1A2POLBHSD17B10 | |
| Acetic Acid SCHEMBL3776954 | 0.97 | ALDH1A1 (0.66) | ALDH1A1CYP2C19CYP1A2POLBHSD17B10 | |
| SCHEMBL489728 | 0.94 | ALDH1A1 (0.63) | ALDH1A1CYP2C19CYP1A2POLBHSD17B10 | |
| SCHEMBL5718021 | 0.87 | POLB (0.62) | ALDH1A1CYP2C19CYP1A2POLBHSD17B10 | |
| SCHEMBL4311418 | 0.85 | POLB (0.61) | ALDH1A1CYP2C19CYP1A2POLBHSD17B10 | |
| SCHEMBL3389758 | 0.85 | ALDH1A1 (0.82) | ALDH1A1CYP2C19CYP1A2POLBHSD17B10 | |
| SCHEMBL6153958 | 0.84 | ALDH1A1 (0.51) | ALDH1A1CYP2C19CYP1A2POLBHSD17B10 | |
| SCHEMBL925084 | 0.83 | ALDH1A1 (0.92) | ALDH1A1CYP2C19CYP1A2POLBHSD17B10 | |
| SCHEMBL3368846 | 0.83 | POLB (0.69) | ALDH1A1CYP2C19CYP1A2POLBHSD17B10 | |
| SCHEMBL18338822 | 0.83 | ALDH1A1 (0.50) | ALDH1A1CYP2C19CYP1A2POLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5595741-A | Aminoalkylmaleimides and hapten and antigen derivatives derived therefrom as well as conjugates with peptides or proteins | BOEHRINGER MANNHEIM GMBH (DE) | 1997-01-21 | — | — | US | claimed |
| CN-117320685-A | Composition for skin protection comprising an antimicrobial agent and a (bio) -alkanediol | 西姆莱斯股份公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-116685300-A | Composition comprising one or more (bio) -alkanediols with an antioxidant | 西姆莱斯股份公司 | 2023-09-01 | — | — | CN | disclosed |
| US-20230265268-A1 | THERMOPLASTIC ELASTOMER COMPOSITION | POLYMAX THERMOPLASTIC ELASTOMERS, LLC | 2023-08-24 | — | — | US | disclosed |
| CN-116583257-A | Compositions comprising (bio) -alkanediols | 西姆莱斯股份公司 | 2023-08-11 | — | — | CN | disclosed |
| US-20230233516-A1 | HIGH PENETRATION COMPOSITIONS AND THEIR APPLICATIONS | TECHFIELDS PHARMA CO., LTD (CN) | 2023-07-27 | — | — | US | disclosed |
| US-11541029-B2 | High penetration compositions and their applications | TECHFIELDS PHARMA CO., LTD. (CN) | 2023-01-03 | — | — | US | disclosed |
| US-8097602-B1 | Method of treating body insect infestation | HOST PHARMACEUTICALS, LLC (US) | 2012-01-17 | — | — | US | disclosed |
| US-20110269689-A1 | HIGH PENETRATION COMPOSITIONS AND THEIR APPLICATIONS | PREMIER RESEARCH INTERNATIONAL, LLC | 2011-11-03 | — | — | US | disclosed |
| EP-2370406-A1 | HIGH PENETRATION COMPOSITIONS AND THEIR APPLICATIONS | Yu, Chongxi (US) | 2011-10-05 | — | — | EP | disclosed |
| US-4614823-A | FOR DETERMINATION OF LIGANDS IN BIOLOGICAL FLUIDS | ABBOTT LABORATORIES (US) | 1986-09-30 | — | — | US | disclosed |
| EP-0195320-A2 | Diagnostic assay using microperoxidase | ABBOTT LABORATORIES (US) | 1986-09-24 | — | — | EP | disclosed |
| US-4581359-A | FOR BRONCHOPULMONARY INSUFFUCIENCY | THE STATE OF OREGON ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY (US) | 1986-04-08 | — | — | US | disclosed |
| US-4510251-A | Fluorescent polarization assay for ligands using aminomethylfluorescein derivatives as tracers | ABBOTT LABORATORIES (US) | 1985-04-09 | — | — | US | disclosed |
| EP-0110186-A1 | Aminomethylfluorescein derivatives | ABBOTT LABORATORIES (US) | 1984-06-13 | — | — | EP | disclosed |
| US-4451652-A | Substituted theophylline salts | ABBOTT LABORATORIES (US) | 1984-05-29 | — | — | US | disclosed |
| US-4425345-A | XANTHINE SOLUBILIZER | SMITH AND NEPHEW ASSOCIATED COMPANIES LIMITED (GB) | 1984-01-10 | — | — | US | disclosed |
| US-4425346-A | ANTIGLAUCOMA AGENTS | SMITH AND NEPHEW ASSOCIATED COMPANIES LIMITED (GB) | 1984-01-10 | — | — | US | disclosed |
| EP-0045617-A2 | Pharmaceutical composition | Smith and Nephew Associated Companies p.l.c. (GB) | 1982-02-10 | — | — | EP | disclosed |
| US-4060617-A | Esters of the ophyllinylacetic acid | Wulfing, Johann A. (DT) | 1977-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269689-A1 | HIGH PENETRATION COMPOSITIONS AND THEIR APPLICATIONS | SLC19A1, HIRA, SLC43A1 | ALDH1A1 829/4885CYP2C19 236/4885CYP1A2 367/4885 |
| US-11541029-B2 | High penetration compositions and their applications | SLC19A1, HIRA, SLC43A1 | ALDH1A1 829/4885CYP2C19 236/4885CYP1A2 367/4885 |
| US-20230233516-A1 | HIGH PENETRATION COMPOSITIONS AND THEIR APPLICATIONS | SLC5A7, SLC19A1, SLC43A1 | ALDH1A1 2302/4885CYP2C19 202/4885CYP1A2 483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.