Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3402036 | 1.00 | ALDH1A1 (0.36) | ALDH1A1LMNATP53 | |
| SCHEMBL12758008 | 0.77 | — | — | |
| SCHEMBL7864340 | 0.77 | — | — | |
| SCHEMBL14852687 | 0.71 | — | — | |
| SCHEMBL17344810 | 0.71 | — | — | |
| SCHEMBL10205381 | 0.71 | — | — | |
| SCHEMBL329115 | 0.71 | — | — | |
| Isobutane SCHEMBL11367071 | 0.68 | — | — | |
| Isobutane SCHEMBL429587 | 0.68 | ALDH1A1 (0.50) | ALDH1A1LMNATP53 | |
| SCHEMBL1377688 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180179204-A1 | INHIBITORS OF LYSINE SPECIFIC DEMETHYLASE-1 | CELGENE QUANTICEL RES INC (US) | 2018-06-28 | — | — | US | disclosed |
| US-20170313702-A1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RESEARCH, INC. (US) | 2017-11-02 | — | — | US | disclosed |
| CN-101925554-B | Shrinkage reducing agent | CONSTR RES & TECH GMBH | 2014-06-18 | — | — | CN | disclosed |
| US-8353983-B2 | Shrinkage reducing agent | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2013-01-15 | — | — | US | disclosed |
| US-20120266782-A9 | Shrinking Reducing Agent | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2012-10-25 | — | — | US | disclosed |
| EP-2247552-B1 | SHRINKAGE REDUCING AGENT | CONSTR RES & TECH GMBH (DE) | 2012-07-11 | — | — | EP | disclosed |
| US-20120125236-A1 | Shrinking Reducing Agent | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2012-05-24 | — | — | US | disclosed |
| CN-101925554-A | Shrinkage reducing agent | CONSTR RES & TECH GMBH | 2010-12-22 | — | — | CN | disclosed |
| EP-2247552-A1 | SHRINKAGE REDUCING AGENT | Construction Research & Technology GmbH (DE) | 2010-11-10 | — | — | EP | disclosed |
| US-20100093865-A1 | SULPHUR-LINKED COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | ACUCELA, INC. (US) | 2010-04-15 | — | — | US | disclosed |
| WO-2009095131-A1 | SHRINKAGE REDUCING AGENT | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2009-08-06 | — | — | WO | disclosed |
| EP-0658602-A1 | Thermoplastic resin composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-06-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180179204-A1 | INHIBITORS OF LYSINE SPECIFIC DEMETHYLASE-1 | KDM1B, KDM1A, KDM3A | ALDH1A1 235/4885LMNA 2879/4885TP53 401/4885 |
| US-20120125236-A1 | Shrinking Reducing Agent | BCL2A1, CCAR2, C1R | ALDH1A1 1955/4885LMNA 333/4885TP53 2529/4885 |
| US-20170313702-A1 | HISTONE DEMETHYLASE INHIBITORS | KDM1B, KDM1A, KDM5A | ALDH1A1 437/4885LMNA 2875/4885TP53 248/4885 |
| US-20100093865-A1 | SULPHUR-LINKED COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | ALDH1A2, MPST, CLN6 | ALDH1A1 314/4885LMNA 3498/4885TP53 3894/4885 |
| US-20120266782-A9 | Shrinking Reducing Agent | BCL2A1, CCAR2, C1R | ALDH1A1 1955/4885LMNA 333/4885TP53 2529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.