Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SIGLEC9 | Q9Y336 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3401176 | 0.82 | CNR1 (0.60) | ALDH1A1HPGDGAAHTR2CCES2 | |
| SCHEMBL3404030 | 0.82 | CNR1 (0.44) | ALDH1A1HPGDGAAHTR2CCES2 | |
| SCHEMBL3404735 | 0.82 | HTR2C (0.48) | ALDH1A1HPGDMEN1KMT2AHTR2C | |
| SCHEMBL3405771 | 0.81 | CNR1 (0.43) | ALDH1A1HPGDHTR2CHRH2HRH1 | |
| SCHEMBL13071667 | 0.81 | HTR2C (0.55) | ALDH1A1HPGDLMNAHTR2CBCHE | |
| SCHEMBL3402581 | 0.81 | CNR1 (0.47) | ALDH1A1HPGDHTR2CCES2 | |
| SCHEMBL3401483 | 0.81 | RAB9A (0.49) | ALDH1A1MEN1KMT2ALMNAMAPK1 | |
| SCHEMBL3402275 | 0.81 | CNR1 (0.43) | ALDH1A1HPGDMEN1KMT2AGAA | |
| SCHEMBL3402410 | 0.81 | CNR1 (0.47) | ALDH1A1HPGDHTR2CCES2PLA2G2A | |
| SCHEMBL3403538 | 0.80 | HTR2C (0.54) | ALDH1A1HPGDHTR2CCES2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728009-B1 | Thiazole amides, imidazole amides and related analogues | NEUROGEN CORPORATION (US) | 2010-06-01 | — | — | US | disclosed |