SCHEMBL3402379

SCHEMBL3402379

CC(=O)c1nc(C)c(C)n1C

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.37
KDM4E B2RXH2 4/20 0.35
HSD17B10 Q99714 1/20 0.33
ALDH1A1 P00352 2/20 0.32
GAA P10253 2/20 0.32
POLB P06746 3/20 0.31
CYP1A2 P05177 2/20 0.31
KMT2A Q03164 1/20 0.31
HTT P42858 1/20 0.30
CYP2C9 P11712 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3696308 0.82 ALDH1A1 (0.36) HSD17B10ALDH1A1GAAHTTMAPT
SCHEMBL22641030 0.80 SMN1; SMN2 (0.35) SMN1; SMN2KDM4ECYP1A2KMT2A
Acetic Acid SCHEMBL28203964 0.73 SMN1; SMN2 (0.37) SMN1; SMN2KDM4EHSD17B10ALDH1A1GAA
SCHEMBL10507092 0.71 ALDH1A1 (0.47) SMN1; SMN2HSD17B10ALDH1A1GAAPOLB
SCHEMBL22135199 0.68 ALDH1A1 (0.35) SMN1; SMN2KDM4EHSD17B10ALDH1A1GAA
SCHEMBL14152308 0.67 CYP1A2 (0.37) SMN1; SMN2KDM4EHSD17B10ALDH1A1POLB
SCHEMBL2871580 0.65
SCHEMBL6115483 0.64 KDM4E (0.35) SMN1; SMN2KDM4EHSD17B10POLBCYP1A2
SCHEMBL26766993 0.64 ALDH1A1 (0.45) SMN1; SMN2KDM4EHSD17B10ALDH1A1POLB
SCHEMBL13924818 0.64 CSNK2A2 (0.42) HSD17B10ALDH1A1CYP1A2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4581071-A1 METHOD FOR PRODUCING A MATERIAL FOR A MEMBRANE, MATERIAL, MEMBRANE AND USE OF A MEMBRANE Forschungszentrum Jülich GmbH (DE) 2025-07-09 EP claimed
WO-2024046712-A1 METHOD FOR PRODUCING A MATERIAL FOR A MEMBRANE, MATERIAL, MEMBRANE AND USE OF A MEMBRANE Forschungszentrum Jülich GmbH (DE) 2024-03-07 WO claimed
EP-4581071-A1 METHOD FOR PRODUCING A MATERIAL FOR A MEMBRANE, MATERIAL, MEMBRANE AND USE OF A MEMBRANE Forschungszentrum Jülich GmbH (DE) 2025-07-09 EP disclosed
WO-2024046712-A1 METHOD FOR PRODUCING A MATERIAL FOR A MEMBRANE, MATERIAL, MEMBRANE AND USE OF A MEMBRANE Forschungszentrum Jülich GmbH (DE) 2024-03-07 WO disclosed
US-8497376-B2 4-Cyano-1H-imidazole-2-carboxylic acid [2-cyclohex-1-enyl-4-(2,6-dioxo-piperidin-4-yl)-phenyl]-amide; tyrosine kinase inhibitor; autoimmune diseases, antiinflammatory, anticarcinogenic agent JANSSEN PHARMACEUTICA N.V. (BE) 2013-07-30 US disclosed
EP-2158199-B1 PIPERIDINE COMPOUNDS AND USES THEREOF ASTRAZENECA AB (SE) 2010-11-17 EP disclosed
EP-2158199-B1 PIPERIDINE COMPOUNDS AND USES THEREOF ASTRAZENECA AB (SE) 2010-11-17 EP disclosed
US-20090105296-A1 INHIBITORS OF C-FMS KINASE JANSSEN PHARMACEUTICA N.V. (BE) 2009-04-23 US disclosed
WO-2008152418-A1 PIPERIDINE COMPOUNDS AND USES THEREOF ASTRAZENECA AB (SE) 2008-12-18 WO disclosed
US-20080312255-A1 PIPERDINE COMPOUNDS AND USES THEREOF-911 ASTRAZENECA AB (SE) 2008-12-18 US disclosed
US-20080312255-A1 PIPERDINE COMPOUNDS AND USES THEREOF-911 ASTRAZENECA AB (SE) 2008-12-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090105296-A1 INHIBITORS OF C-FMS KINASE MUSK, FRK, FES SMN1; SMN2 2358/4885KDM4E 1770/4885HSD17B10 4777/4885
US-20080312255-A1 PIPERDINE COMPOUNDS AND USES THEREOF-911 NISCH, PIR, QDPR SMN1; SMN2 2282/4885KDM4E 3497/4885HSD17B10 4653/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.