SCHEMBL340240

SCHEMBL340240

NCCNCCC[SiH2]C1CCCCO1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.34
CA6 P23280 3/20 0.34
CA7 P43166 3/20 0.34
CA9 Q16790 3/20 0.34
CA14 Q9ULX7 3/20 0.34
CA5B Q9Y2D0 3/20 0.34
CA2 P00918 2/20 0.34
CA3 P07451 2/20 0.34
CA4 P22748 2/20 0.34
CA5A P35218 2/20 0.34
MEN1 O00255 1/20 0.32
RECQL P46063 1/20 0.32
KMT2A Q03164 1/20 0.32
LMNA P02545 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
CA1 P00915 1/20 0.31
ALOX15 P16050 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TP53 P04637 1/20 0.31
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3966618 0.90
SCHEMBL183520 0.86 SIGMAR1 (0.32)
SCHEMBL16863076 0.84 MAPT (0.31)
SCHEMBL9636969 0.83 SIGMAR1 (0.34)
SCHEMBL513814 0.81
SCHEMBL16684655 0.80 SIGMAR1 (0.37)
SCHEMBL6232848 0.78 CA12 (0.36) CA12CA6CA7CA9CA14
SCHEMBL9388510 0.78
SCHEMBL16280332 0.75
SCHEMBL1004639 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110741023-B Storage stable fast setting coating system free of volatile base 罗门哈斯公司 2021-10-15 CN claimed
US-11118080-B2 Reinforcement barrier coatings SUN CHEMICAL CORPORATION (US) 2021-09-14 US claimed
CN-109562865-B Barrier-enhancing coating 太阳化学公司 2021-07-30 CN claimed
CN-110741023-A Storage stable fast setting coating system free of volatile base 罗门哈斯公司 2020-01-31 CN claimed
US-20190352530-A1 REINFORCEMENT BARRIER COATINGS SUN CHEMICAL CORPORATION (US) 2019-11-21 US claimed
EP-3497024-A1 REINFORCEMENT BARRIER COATINGS Sun Chemical Corporation (US) 2019-06-19 EP claimed
US-8052776-B2 Poly(amino-alcohol)-silica hybrid compositions and membranes CORNING INCORPORATED (US) 2011-11-08 US claimed
US-20100300289-A1 POLY(AMINO-ALCOHOL)-SILICA HYBRID COMPOSITIONS AND MEMBRANES CORNING INCORPORATED 2010-12-02 US claimed
WO-2010138489-A1 POLY(AMINO-ALCOHOL)-SILICA HYBRID COMPOSITIONS AND MEMBRANES CORNING INCORPORATED (US) 2010-12-02 WO claimed
WO-2008081348-A2 METHOD AND COMPOSITION FOR PERMANENTLY SHAPING HAIR THE PROCTER & GAMBLE COMPANY (US) 2008-07-10 WO claimed
WO-2008012732-A2 METHOD AND COMPOSITION FOR PERMANENTLY SHAPING HAIR THE PROCTER & GAMBLE COMPANY (US) 2008-01-31 WO claimed
US-20080025938-A1 Method and composition for permanently shaping hair PROCTER & GAMBLE COMPANY, THE 2008-01-31 US claimed
US-20080025939-A1 Method and composition for permanently shaping hair PROCTER & GAMBLE COMPANY, THE 2008-01-31 US claimed
WO-2008012731-A2 METHOD AND COMPOSITION FOR PERMANENTLY SHAPING HAIR THE PROCTER & GAMBLE COMPANY (US) 2008-01-31 WO claimed
EP-1880707-A1 Method and composition for permanently shaping hair Wella Aktiengesellschaft (DE) 2008-01-23 EP claimed
EP-1880710-A1 Method and composition for permanently shaping hair Wella Aktiengesellschaft (DE) 2008-01-23 EP claimed
EP-1880709-A1 Method and composition for permanently shaping hair Wella Aktiengesellschaft (DE) 2008-01-23 EP claimed
EP-1880706-A1 Method and composition for permanently shaping hair Wella Aktiengesellschaft (DE) 2008-01-23 EP claimed
EP-1880708-A1 Method and composition for permanently shaping hair Wella Aktiengesellschaft (DE) 2008-01-23 EP claimed
US-6506715-B1 Aqueous emulsion containing an anionic surfactant, a silicone oil, an amino-functional silicone, a wax, and a cationic emulsifier TURTLE WAX, INC. 2003-01-14 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080025938-A1 Method and composition for permanently shaping hair KRT18, HHAT, AADAT CA12 426/4885CA6 166/4885CA7 234/4885
US-20080025939-A1 Method and composition for permanently shaping hair DNMT3A, DNMT1, TET2 CA12 673/4885CA6 611/4885CA7 600/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.