Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6908442 | 0.86 | TSHR (0.36) | TSHRACHEALDH1A1HPGDALOX12 | |
| SCHEMBL4660563 | 0.85 | TRPA1 (0.38) | TSHRALDH1A1CYP3A4TDP1NPC1 | |
| SCHEMBL4660560 | 0.77 | TP53 (0.38) | ALDH1A1TDP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29042403 | 0.72 | TSHR (0.35) | TSHRACHEALDH1A1NPC1RAB9A | |
| SCHEMBL1313948 | 0.72 | TSHR (0.43) | TSHRACHEALDH1A1CYP3A4TDP1 | |
| SCHEMBL585656 | 0.70 | ESR1 (0.32) | ALDH1A1 | |
| SCHEMBL1314878 | 0.67 | TSHR (0.38) | TSHRACHEALDH1A1CYP3A4TDP1 | |
| SCHEMBL1314101 | 0.67 | TSHR (0.38) | TSHRACHEALDH1A1CYP3A4TDP1 | |
| SCHEMBL3804301 | 0.67 | SMN1; SMN2 (0.45) | TSHRACHEALDH1A1HPGDTDP1 | |
| SCHEMBL3402601 | 0.67 | TDP1 (0.35) | TSHRACHEALDH1A1HPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3408314-A1 | POLYOLEFIN FILM WITH IMPROVED TOUGHNESS | Univation Technologies, LLC (US) | 2018-12-05 | — | — | EP | disclosed |
| WO-2017132092-A1 | POLYOLEFIN FILM WITH IMPROVED TOUGHNESS | UNIVATION TECHNOLOGIES, LLC (US) | 2017-08-03 | — | — | WO | disclosed |
| EP-2247630-A1 | MODIFIED CHROMIUM-BASED CATALYSTS AND POLYMERIZATION PROCESSES FOR USING THE SAME | Univation Technologies, LLC (US) | 2010-11-10 | — | — | EP | disclosed |
| WO-2009108174-A1 | MODIFIED CHROMIUM-BASED CATALYSTS AND POLYMERIZATION PROCESSES FOR USING THE SAME | UNIVATION TECHNOLOGIES, LLC (US) | 2009-09-03 | — | — | WO | disclosed |
| EP-1003792-A1 | A PROCESS FOR THE PREPARATION OF POLYETHYLENE | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999009075-A1 | A PROCESS FOR THE PREPARATION OF POLYETHYLENE | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1999-02-25 | — | — | WO | disclosed |