SCHEMBL6908442

SCHEMBL6908442

Cc1ccccc1[Si](O[Cr](=O)(=O)O[Si](c1ccccc1C)(c1ccccc1C)c1ccccc1C)(c1ccccc1C)c1ccccc1C

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.36
ACHE P22303 2/20 0.36
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ALDH1A1 P00352 2/20 0.31
HPGD P15428 1/20 0.31
ALOX12 P18054 1/20 0.31
ESR1 P03372 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3402602 0.86 TSHR (0.35) TSHRACHEMEN1NPC1RAB9A
SCHEMBL7028689 0.84 TRPA1 (0.34) TSHRSMN1; SMN2
SCHEMBL29042403 0.82 TSHR (0.35) TSHRACHEMEN1NPC1RAB9A
SCHEMBL8770575 0.76 ADRA2A (0.35) MEN1KMT2AHPGD
SCHEMBL975316 0.76 TP53 (0.34) MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL1313948 0.73 TSHR (0.43) TSHRACHEMEN1NPC1RAB9A
SCHEMBL4660563 0.71 TRPA1 (0.38) TSHRMEN1NPC1RAB9AKMT2A
SCHEMBL56597 0.69 ALDH1A1 (0.32) ALDH1A1
SCHEMBL3804301 0.68 SMN1; SMN2 (0.45) TSHRACHEMEN1NPC1RAB9A
SCHEMBL1314101 0.68 TSHR (0.38) TSHRACHEMEN1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0626256-B1 Hollow multi-layer molding MITSUBISHI CHEM CORP (JP) 1997-08-06 EP claimed
US-5443874-A Laminate including high molecular weight polyethylene formed with reducing agent and silyl chromate catalyst, barrier layer of polyamide, saponified ethylene-vinyl acetate, thermoplastic polyester or blend, adhesive of acid-modified polyethylene MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1995-08-22 US claimed
EP-0626256-A1 Hollow multi-layer molding MITSUBISHI CHEMICAL CORPORATION (JP) 1994-11-30 EP claimed
EP-3802640-B1 UNIMODAL POLYETHYLENE COPOLYMER AND FILM THEREOF UNIVATION TECH LLC (US) 2025-10-22 EP disclosed
US-12240927-B2 Unimodal polyethylene copolymer and film thereof UNIVATION TECHNOLOGIES, LLC (US) 2025-03-04 US disclosed
US-20250019475-A1 UNIMODAL POLYETHYLENE COPOLYMER AND FILM THEREOF UNIVATION TECHNOLOGIES, LLC 2025-01-16 US disclosed
WO-2025007440-A1 CHROMIUM COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF, AND CATALYTIC OXIDATION METHOD FOR BENZYL ALCOHOL COMPOUND 中国石油天然气股份有限公司 2025-01-09 WO disclosed
CN-119264188-A Chromium compound, preparation method and application thereof, and benzyl alcohol compound catalytic oxidation method 中国石油天然气股份有限公司 2025-01-07 CN disclosed
US-12173096-B2 Unimodal polyethylene copolymer and film thereof UNIVATION TECHNOLOGIES, LLC (US) 2024-12-24 US disclosed
US-20240228683-A1 UNIMODAL POLYETHYLENE COPOLYMER AND FILM THEREOF UNIVATION TECHNOLOGIES, LLC 2024-07-11 US disclosed
US-12012472-B2 Unimodal polyethylene copolymer and film thereof UNIVATION TECHNOLOGIES, LLC (US) 2024-06-18 US disclosed
US-6673736-B2 GAS PHASE ADDITION POLYMERIZATION IN THE PRESENCE OF CATALYSTS COMPRISING CHROMIC ACID, BIS-/TRIPHENYLSILYL/ ESTER, ON SILICA SUPPORTS, TO FOM NONCRACKING HIGH MOLECULAR WEIGHT FILMS CHEVRON CHEMICAL COMPANY LLC 2004-01-06 US disclosed
US-20030129341-A1 CHROMATE ESTER CATALYST AND METHOD OF USING SAME TO PRODUCE HIGH PERFORMANCE POLYETHYLENE PRODUCTS CHEVRON CHEMICAL COMPANY LLC 2003-07-10 US disclosed
US-6326443-B1 COORDINATION POLYMERIZATION CATALYST SHOWA DENKO K.K. (JP) 2001-12-04 US disclosed
EP-1155054-A1 IMPROVED CHROMATE ESTER CATALYST AND METHOD OF USING SAME TO PRODUCE HIGH PERFORMANCE POLYETHYLENE PRODUCTS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2001-11-21 EP disclosed
WO-2000039173-A1 IMPROVED CHROMATE ESTER CATALYST AND METHOD OF USING SAME TO PRODUCE HIGH PERFORMANCE POLYETHYLENE PRODUCTS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2000-07-06 WO disclosed
EP-0931797-A1 PROCESS FOR PREPARING ETHYLENE POLYMER AND CATALYST USED THEREFOR SHOWA DENKO KABUSHIKI KAISHA (JP) 1999-07-28 EP disclosed
EP-0626256-B1 Hollow multi-layer molding MITSUBISHI CHEM CORP (JP) 1997-08-06 EP disclosed
US-5443874-A Laminate including high molecular weight polyethylene formed with reducing agent and silyl chromate catalyst, barrier layer of polyamide, saponified ethylene-vinyl acetate, thermoplastic polyester or blend, adhesive of acid-modified polyethylene MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1995-08-22 US disclosed
EP-0626256-A1 Hollow multi-layer molding MITSUBISHI CHEMICAL CORPORATION (JP) 1994-11-30 EP disclosed