Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL585656 | 0.77 | ESR1 (0.32) | ALDH1A1LMNACES2CES1 | |
| SCHEMBL475824 | 0.70 | LMNA (0.48) | TDP1ACHEALDH1A1LMNACES2 | |
| SCHEMBL3867444 | 0.69 | ACHE (0.44) | TDP1ACHEALDH1A1LMNATSHR | |
| SCHEMBL7862064 | 0.67 | ACHE (0.42) | TDP1ACHEALDH1A1LMNATSHR | |
| SCHEMBL3402602 | 0.67 | TSHR (0.35) | TDP1ACHEALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL4707391 | 0.67 | ACHE (0.36) | TDP1ACHEALDH1A1LMNACES2 | |
| SCHEMBL4643859 | 0.65 | CYP2C19 (0.36) | TDP1ALDH1A1LMNACES2CES1 | |
| SCHEMBL3873557 | 0.65 | ACHE (0.46) | TDP1ACHEALDH1A1LMNATSHR | |
| SCHEMBL3867374 | 0.64 | ACHE (0.38) | TDP1ACHEALDH1A1SMN1; SMN2HTT | |
| SCHEMBL13870133 | 0.64 | ACHE (0.46) | TDP1ACHEALDH1A1LMNACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3408314-A1 | POLYOLEFIN FILM WITH IMPROVED TOUGHNESS | Univation Technologies, LLC (US) | 2018-12-05 | — | — | EP | disclosed |
| WO-2017132092-A1 | POLYOLEFIN FILM WITH IMPROVED TOUGHNESS | UNIVATION TECHNOLOGIES, LLC (US) | 2017-08-03 | — | — | WO | disclosed |
| EP-2247630-A1 | MODIFIED CHROMIUM-BASED CATALYSTS AND POLYMERIZATION PROCESSES FOR USING THE SAME | Univation Technologies, LLC (US) | 2010-11-10 | — | — | EP | disclosed |
| WO-2009108174-A1 | MODIFIED CHROMIUM-BASED CATALYSTS AND POLYMERIZATION PROCESSES FOR USING THE SAME | UNIVATION TECHNOLOGIES, LLC (US) | 2009-09-03 | — | — | WO | disclosed |
| EP-1003792-A1 | A PROCESS FOR THE PREPARATION OF POLYETHYLENE | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999009075-A1 | A PROCESS FOR THE PREPARATION OF POLYETHYLENE | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1999-02-25 | — | — | WO | disclosed |