Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 14/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 12/20 | 0.46 |
| ▸ | MBTD1 | Q05BQ5 | 6/20 | 0.46 |
| ▸ | TP53BP1 | Q12888 | 3/20 | 0.45 |
| ▸ | CCR5 | P51681 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL4 | Q8NA19 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3403915 | 0.91 | KMT2A (0.48) | L3MBTL3L3MBTL1CCR5MEN1KMT2A | |
| SCHEMBL3400065 | 0.82 | L3MBTL3 (0.48) | L3MBTL3L3MBTL1MBTD1TP53BP1MEN1 | |
| SCHEMBL3404126 | 0.82 | L3MBTL3 (0.48) | L3MBTL3L3MBTL1MBTD1TP53BP1MEN1 | |
| SCHEMBL3405473 | 0.82 | KDM4E (0.47) | L3MBTL3L3MBTL1CCR5MEN1KMT2A | |
| SCHEMBL2202742 | 0.79 | KMT2A (0.50) | L3MBTL3L3MBTL1MBTD1TP53BP1MEN1 | |
| SCHEMBL3401127 | 0.78 | LMNA (0.50) | L3MBTL1MEN1KMT2ALMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL2201681 | 0.78 | KMT2A (0.51) | L3MBTL3L3MBTL1MBTD1TP53BP1KMT2A | |
| SCHEMBL2201429 | 0.77 | KMT2A (0.46) | L3MBTL3L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL2201747 | 0.76 | KMT2A (0.47) | L3MBTL3L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL2200707 | 0.76 | KMT2A (0.52) | L3MBTL3L3MBTL1MBTD1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728009-B1 | Thiazole amides, imidazole amides and related analogues | NEUROGEN CORPORATION (US) | 2010-06-01 | — | — | US | disclosed |