Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGLEC9 | Q9Y336 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13779957 | 0.83 | HTR2C (0.55) | SIGLEC9PARP1ALDH1A1MEN1KMT2A | |
| SCHEMBL3405665 | 0.81 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2ALMNAMAPK1 | |
| SCHEMBL3454926 | 0.81 | ALDH1A1 (0.59) | SIGLEC9ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL29944007 | 0.81 | ALDH1A1 (0.59) | SIGLEC9ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL3405399 | 0.79 | CNR1 (0.57) | PARP1ALDH1A1HRH3CNR1HTR2C | |
| SCHEMBL3404912 | 0.79 | CNR1 (0.51) | PARP1HRH3CNR1HTR2C | |
| SCHEMBL3401781 | 0.79 | CNR1 (0.70) | PARP1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL3404209 | 0.78 | HTR2C (0.49) | PARP1ALDH1A1HPGDHRH3CNR1 | |
| SCHEMBL3405573 | 0.78 | HTR2C (0.52) | SIGLEC9PARP1ALDH1A1MEN1KMT2A | |
| SCHEMBL3405446 | 0.78 | CNR1 (0.47) | PARP1ALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728009-B1 | Thiazole amides, imidazole amides and related analogues | NEUROGEN CORPORATION (US) | 2010-06-01 | — | — | US | disclosed |