Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.41 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 7/20 | 0.41 |
| ▸ | CA2 | P00918 | 7/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17468120 | 0.96 | TDP1 (0.49) | TDP1MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL7612049 | 0.95 | TDP1 (0.51) | TDP1MEN1KMT2AGAAMAN2B1 | |
| SCHEMBL337313 | 0.95 | TDP1 (0.51) | TDP1MEN1KMT2AGAAMAN2B1 | |
| SCHEMBL22431353 | 0.95 | TDP1 (0.51) | TDP1MEN1KMT2AGAAMAN2B1 | |
| SCHEMBL17381378 | 0.95 | TDP1 (0.51) | TDP1MEN1KMT2AGAAMAN2B1 | |
| SCHEMBL3122796 | 0.92 | ALDH1A1 (0.44) | TDP1MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL22402873 | 0.90 | TDP1 (0.47) | TDP1SMN1; SMN2MAN2B1MAOAMAOB | |
| SCHEMBL3474501 | 0.90 | TDP1 (0.47) | TDP1SMN1; SMN2MAN2B1MAOAMAOB | |
| SCHEMBL10071724 | 0.90 | CA1 (0.42) | TDP1MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL25940770 | 0.89 | TDP1 (0.42) | TDP1MEN1KMT2AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230279476-A1 | NOVEL ACRYLATE DERIVATIVES AND USES THEREOF | EXPANSION TECHNOLOGIES (US) | 2023-09-07 | — | — | US | disclosed |
| US-20230279476-A1 | NOVEL ACRYLATE DERIVATIVES AND USES THEREOF | EXPANSION TECHNOLOGIES (US) | 2023-09-07 | — | — | US | disclosed |
| US-11345715-B2 | Biologically active molecules, conjugates thereof, and therapeutic uses | REGENERON PHARMACEUTICALS, INC. (US) | 2022-05-31 | — | — | US | disclosed |
| US-20200277306-A1 | BIOLOGICALLY ACTIVE MOLECULES, CONJUGATES THEREOF, AND THERAPEUTIC USES | REGENERON PHARMACEUTICALS, INC. | 2020-09-03 | — | — | US | disclosed |
| US-10570151-B2 | Biologically active molecules, conjugates thereof, and therapeutic uses | REGENERON PHARMACEUTICALS, INC. (US) | 2020-02-25 | — | — | US | disclosed |
| WO-2019032956-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-02-14 | — | — | WO | disclosed |
| US-20170073468-A1 | METHOD FOR PREPARING FUNCTIONALIZED POLYMERS FROM POLYMER ALCOHOLS | NEKTAR THERAPEUTICS | 2017-03-16 | — | — | US | disclosed |
| US-20160030591-A1 | BIOLOGICALLY ACTIVE MOLECULES, CONJUGATES THEREOF, AND THERAPEUTIC USES | REGENERON PHARMACEUTICALS, INC. | 2016-02-04 | — | — | US | disclosed |
| US-20160030591-A1 | BIOLOGICALLY ACTIVE MOLECULES, CONJUGATES THEREOF, AND THERAPEUTIC USES | REGENERON PHARMACEUTICALS, INC. | 2016-02-04 | — | — | US | disclosed |
| WO-2014145090-A1 | BIOLOGICALLY ACTIVE MOLECULES, CONJUGATES THEREOF, AND THERAPEUTIC USES | REGENERON PHARMACEUTICALS, INC. (US) | 2014-09-18 | — | — | WO | disclosed |
| US-8735411-B2 | Macrocyclic benzofused pyrimidine derivatives | ABBVIE INC. (US) | 2014-05-27 | — | — | US | disclosed |
| US-20140073802-A1 | MALEIMIDYL POLYMER DERIVATIVES | NEKTAR THERAPEUTICS (US) | 2014-03-13 | — | — | US | disclosed |
| US-20120252741-A1 | NOVEL SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | BIOMARIN PHARMACEUTICAL INC. (US) | 2012-10-04 | — | — | US | disclosed |
| US-20100105607-A1 | NOVEL SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | LEAD THERAPEUTICS, INC. (US) | 2010-04-29 | — | — | US | disclosed |
| WO-2010048340-A2 | NOVEL SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | LEAD THERAPEUTICS, INC. (US) | 2010-04-29 | — | — | WO | disclosed |
| US-20080188452-A1 | Macrocyclic Benzofused Pyrimidine Derivatives | ABBVIE INC. | 2008-08-07 | — | — | US | disclosed |
| US-20080176889-A1 | 9-anilinoacridine alkylating agents | ACADEMIA SINICA (TW) | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230279476-A1 | NOVEL ACRYLATE DERIVATIVES AND USES THEREOF | DCLRE1A, ACR, PHAX | TDP1 182/4885MEN1 4026/4885KMT2A 3464/4885 |
| US-10570151-B2 | Biologically active molecules, conjugates thereof, and therapeutic uses | CD47, CD44, ACP1 | TDP1 1597/4885MEN1 1973/4885KMT2A 3124/4885 |
| US-20160030591-A1 | BIOLOGICALLY ACTIVE MOLECULES, CONJUGATES THEREOF, AND THERAPEUTIC USES | CD47, CD44, ACP1 | TDP1 1597/4885MEN1 1973/4885KMT2A 3124/4885 |
| US-20100105607-A1 | NOVEL SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | ASNS, ALG8, ALG1 | TDP1 4811/4885MEN1 2517/4885KMT2A 556/4885 |
| US-20080188452-A1 | Macrocyclic Benzofused Pyrimidine Derivatives | DPYD, TYMS, UMPS | TDP1 604/4885MEN1 2195/4885KMT2A 2423/4885 |
| US-11345715-B2 | Biologically active molecules, conjugates thereof, and therapeutic uses | CD47, CD44, ACP1 | TDP1 1597/4885MEN1 1973/4885KMT2A 3124/4885 |
| US-20200277306-A1 | BIOLOGICALLY ACTIVE MOLECULES, CONJUGATES THEREOF, AND THERAPEUTIC USES | CD47, CD44, ACP1 | TDP1 1597/4885MEN1 1973/4885KMT2A 3124/4885 |
| US-20080176889-A1 | 9-anilinoacridine alkylating agents | BCL9, MCL1, BCL9L | TDP1 223/4885MEN1 1814/4885KMT2A 288/4885 |
| US-20120252741-A1 | NOVEL SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | ASNS, DNPEP, ALG8 | TDP1 4719/4885MEN1 3339/4885KMT2A 442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.