SCHEMBL3403152

SCHEMBL3403152

COc1ccccc1-c1ncc[nH]1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA1A P35348 1/20 0.54
PDE5A O76074 4/20 0.51
AURKA O14965 1/20 0.51
DCUN1D1 Q96GG9 2/20 0.50
SMPD3 Q9NY59 1/20 0.50
ALDH1A1 P00352 2/20 0.49
CSNK1A1 P48729 1/20 0.49
TYRO3 Q06418 1/20 0.49
DYRK1B Q9Y463 1/20 0.49
GAA P10253 1/20 0.49
MTOR P42345 1/20 0.48
ADK P55263 1/20 0.48
NISCH Q9Y2I1 1/20 0.48
ALPL P05186 1/20 0.46
MC4R P32245 2/20 0.46
CCNB2 O95067 1/20 0.45
CDK1 P06493 1/20 0.45
CCNB1 P14635 1/20 0.45
GSK3A P49840 1/20 0.45
GSK3B P49841 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29360270 1.00 ADRA1A (0.54) ADRA1APDE5AAURKADCUN1D1SMPD3
Oxalic Acid SCHEMBL31679096 0.91 CSNK1A1 (0.52) ADRA1APDE5AAURKADCUN1D1SMPD3
SCHEMBL3923733 0.85 MC4R (0.46) ADRA1APDE5AAURKASMPD3ALDH1A1
SCHEMBL6003173 0.85 MGAM (0.47) ADRA1ASMPD3ALDH1A1CSNK1A1TYRO3
SCHEMBL31429595 0.83 SMPD3 (0.56) ADRA1ASMPD3ALDH1A1CSNK1A1TYRO3
SCHEMBL3403159 0.83 ADRA1A (0.58) ADRA1APDE5AALDH1A1CSNK1A1TYRO3
SCHEMBL8541523 0.82 ADRA1A (0.54) ADRA1APDE5ACSNK1A1TYRO3DYRK1B
SCHEMBL6001642 0.81 ADRA1A (0.50) ADRA1APDE5AAURKASMPD3ALDH1A1
SCHEMBL9287236 0.80 NISCH (0.64) ADRA1AALDH1A1CSNK1A1TYRO3DYRK1B
SCHEMBL6003238 0.79 PDE2A (0.55) ADRA1ASMPD3ALDH1A1GAAALPL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106249545-B It is a kind of can selfreparing photosensitive dry film solder mask 杭州福斯特应用材料股份有限公司 2019-06-25 CN claimed
CN-108490737-A A kind of photosensitive polymer combination and application thereof 浙江福斯特新材料研究院有限公司 2018-09-04 CN claimed
CN-101735217-B Application of imidazole [4,5-f][1,10] phenanthroline and derivative thereof to preparation of antineoplastic drug UNIV GUANGDONG PHARM 2012-09-26 CN claimed
CN-101863894-B Tanshinone II A derivative and preparation method and application thereof UNIV GUANGDONG PHARM 2012-07-18 CN claimed
CN-101863894-A Tanshinone II A derivative and preparation method and application thereof GUANGDONG PHARMACEUTICAL UNIVERSITY 2010-10-20 CN claimed
CN-101735217-A Application of imidazole [4,5-f][1,10] phenanthroline and derivative thereof to preparation of antineoplastic drug UNIV GUANGDONG PHARM 2010-06-16 CN claimed
US-4339448-A Imidazole-copper complex compounds and fungicides containing them BASF AKTIENGESELLSCHAFT (DE) 1982-07-13 US claimed
US-11976047-B1 4,5-bis(4-bromo-phenyl)-1-hexyl-2-(2- methoxyphenyl)-1H-imidazole as an antimicrobial compound King Faisal University (SA) 2024-05-07 US disclosed
CN-116224716-A Photoresist for preparing HJT solar cell copper grid and preparation method thereof 苏州皓申智能科技有限公司 2023-06-06 CN disclosed
CN-115636861-B Deoxynucleoside modified ruthenium complex and preparation method and application thereof 广州鲁比生物科技有限公司 2023-05-16 CN disclosed
CN-115636861-A Deoxynucleoside modified ruthenium complex and preparation method and application thereof 广州鲁比生物科技有限公司 2023-01-24 CN disclosed
CN-112851670-B Simple synthesis method of 3-polyfluoroalkyl substituted imidazo [1,2-a ] pyridine 深圳大学 2022-01-04 CN disclosed
US-11090289-B2 Compositions and methods for blocking sodium channels UNIVERSITY OF VIRGINIA PATENT FOUNDATION 2021-08-17 US disclosed
EP-1159316-A1 PROCESS FOR PRODUCING POLYETHYLENE EASTMAN CHEMICAL COMPANY (US) 2001-12-05 EP disclosed
WO-2000058372-A1 PROCESS FOR PRODUCING POLYOLEFINS EASTMAN CHEMICAL COMPANY (US) 2000-10-05 WO disclosed
WO-2000052069-A1 PROCESS FOR PRODUCING POLYETHYLENE EASTMAN CHEMICAL COMPANY (US) 2000-09-08 WO disclosed
WO-2000052068-A1 PROCESS FOR PRODUCING POLYETHYLENE EASTMAN CHEMICAL COMPANY (US) 2000-09-08 WO disclosed
CN-1011629-B XEROPRINTING WITH PHOTOPOLYMER MASTER DU PONT (US) 1991-02-13 CN disclosed
CN-87103295-A Adopt the xerography of photosensitive polymer template 1987-11-11 CN disclosed
US-4339448-A Imidazole-copper complex compounds and fungicides containing them BASF AKTIENGESELLSCHAFT (DE) 1982-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11090289-B2 Compositions and methods for blocking sodium channels SCN3A, SCN1B, SCN2B ADRA1A 533/4885PDE5A 295/4885AURKA 3842/4885
US-11976047-B1 4,5-bis(4-bromo-phenyl)-1-hexyl-2-(2- methoxyphenyl)-1H-imidazole as an antimicrobial compound BRD4, CASP4, BET1 ADRA1A 3642/4885PDE5A 3877/4885AURKA 1987/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.