Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | MC4R | P32245 | 2/20 | 0.46 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3403152 | 0.85 | ADRA1A (0.54) | GAAMC4RSMPD3ADRA1ATUBB4A | |
| SCHEMBL29360270 | 0.85 | ADRA1A (0.54) | GAAMC4RSMPD3ADRA1ATUBB4A | |
| SCHEMBL24026507 | 0.84 | ADRA1A (0.43) | MC4RSMPD3ADRA1AADRA2AADRA2C | |
| SCHEMBL3923733 | 0.84 | MC4R (0.46) | MC4RSMPD3ADRA1AADRA2AADRA2C | |
| SCHEMBL31429595 | 0.83 | SMPD3 (0.56) | GAAMC4RSMPD3ADRA1AADRA2A | |
| SCHEMBL20150086 | 0.80 | TAAR1 (0.46) | MC4RSMPD3ADRA1AADRA2AADRA2C | |
| SCHEMBL20230883 | 0.80 | ALDH1A1 (0.39) | MC4RSMPD3ADRA1AADRA2AADRA2C | |
| SCHEMBL24026441 | 0.80 | HTR1A (0.47) | MC4RSMPD3ADRA1AADRA2AADRA2C | |
| Oxalic Acid SCHEMBL31679096 | 0.77 | CSNK1A1 (0.52) | SMPD3ADRA1AADRA2AADRA2CALDH1A1 | |
| SCHEMBL21375828 | 0.76 | ADRA2A (0.39) | MC4RSMPD3ADRA1AADRA2AADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |