Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | DHFR | P00374 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3402973 | 0.99 | EGFR (0.50) | EGFRMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27626574 | 0.81 | L3MBTL1 (0.63) | EGFRMAPTRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL3407436 | 0.81 | RAB9A (0.65) | MAPTRAB9ANPC1SMN1; SMN2GAA | |
| SCHEMBL3406120 | 0.81 | AOC3 (0.61) | MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL970695 | 0.78 | AOC3 (0.47) | EGFRMAPTSMN1; SMN2L3MBTL1GAA | |
| SCHEMBL4875145 | 0.77 | L3MBTL1 (0.51) | EGFRMAPTSMN1; SMN2L3MBTL1DHFR | |
| Hydrochloric Acid SCHEMBL973152 | 0.77 | AOC3 (0.46) | EGFRMAPTL3MBTL1GAADHFR | |
| SCHEMBL972553 | 0.77 | EGFR (0.43) | EGFRMAPTSMN1; SMN2L3MBTL1GAA | |
| Hydrochloric Acid SCHEMBL4874159 | 0.76 | L3MBTL1 (0.56) | EGFRMAPTRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL4871149 | 0.75 | CYP1A2 (0.76) | EGFRMAPTRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252604-A1 | THIAZOLE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-Tech Ueno, Ltd. (JP) | 2010-11-24 | — | — | EP | disclosed |
| WO-2009096609-A1 | THIAZOLE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-TECH UENO, LTD. (JP) | 2009-08-06 | — | — | WO | disclosed |