Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 7/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD5 | P21918 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.43 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1345320 | 0.85 | HRH1 (0.51) | SMN1; SMN2HPGDHRH1L3MBTL1DRD2 | |
| SCHEMBL5478147 | 0.84 | HPGD (0.50) | SMN1; SMN2HPGDHRH1L3MBTL1DRD2 | |
| SCHEMBL5478146 | 0.84 | HPGD (0.50) | SMN1; SMN2HPGDHRH1L3MBTL1DRD2 | |
| SCHEMBL11607227 | 0.81 | HPGD (0.47) | SMN1; SMN2HPGDHRH1L3MBTL1DRD2 | |
| SCHEMBL27644538 | 0.81 | HPGD (0.51) | SMN1; SMN2HPGDHRH1L3MBTL1DRD2 | |
| SCHEMBL531084 | 0.81 | PTGS2 (0.54) | SMN1; SMN2HPGDHRH1L3MBTL1DRD2 | |
| SCHEMBL28886357 | 0.80 | L3MBTL1 (0.46) | HPGDL3MBTL1TSHR | |
| SCHEMBL28860367 | 0.78 | HPGD (0.45) | SMN1; SMN2HPGDHRH1L3MBTL1DRD2 | |
| SCHEMBL4342753 | 0.77 | THRA (0.57) | SMN1; SMN2HPGDHRH1L3MBTL1DRD2 | |
| SCHEMBL30778391 | 0.77 | HRH1 (0.47) | SMN1; SMN2HPGDHRH1L3MBTL1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10675278-B2 | Crush resistant delayed-release dosage forms | Grünenthal GmbH (DE) | 2020-06-09 | — | — | US | disclosed |
| US-20180369235-A1 | CRUSH RESISTANT DELAYED-RELEASE DOSAGE FORMS | Grünenthal GmbH (DE) | 2018-12-27 | — | — | US | disclosed |
| US-20170312271-A1 | CRUSH RESISTANT DELAYED-RELEASE DOSAGE FORMS | Grünenthal GmbH (DE) | 2017-11-02 | — | — | US | disclosed |
| US-9750701-B2 | Pharmaceutical dosage form | Grünenthal GmbH (DE) | 2017-09-05 | — | — | US | disclosed |
| US-20160199305-A1 | PHARMACEUTICAL DOSAGE FORM | Grünenthal GmbH (DE) | 2016-07-14 | — | — | US | disclosed |
| US-20160184297-A1 | CRUSH RESISTANT DELAYED-RELEASE DOSAGE FORMS | Grünenthal GmbH (DE) | 2016-06-30 | — | — | US | disclosed |
| US-20160120810-A1 | CRUSH RESISTANT DELAYED-RELEASE DOSAGE FORMS | Grünenthal GmbH (DE) | 2016-05-05 | — | — | US | disclosed |
| US-20150374630-A1 | Crush resistant delayed-release dosage forms | GRUENENTHAL GMBH (DE) | 2015-12-31 | — | — | US | disclosed |
| US-20150290138-A1 | Crush resistant delayed-release dosage forms | Grünenthal GmbH (DE) | 2015-10-15 | — | — | US | disclosed |
| US-20140322323-A1 | PHARMACEUTICAL DOSAGE FORM | Grünenthal GmbH (DE) | 2014-10-30 | — | — | US | disclosed |
| US-20140322311-A1 | CRUSH RESISTAN DELAYED-RELEASE DOSAGE FORM | Grünenthal GmbH (DE) | 2014-10-30 | — | — | US | disclosed |
| US-20140079780-A1 | Crush resistant delayed-release dosage forms | GRUENENTHAL GMBH (DE) | 2014-03-20 | — | — | US | disclosed |
| US-20130251759-A1 | PHARMACEUTICAL DOSAGE FORM | GRUENENTHAL GMBH (DE) | 2013-09-26 | — | — | US | disclosed |
| US-8383152-B2 | Pharmaceutical dosage form | GRUENENTHAL GMBH (DE) | 2013-02-26 | — | — | US | disclosed |
| EP-2249811-A1 | PHARMACEUTICAL DOSAGE FORM | Grünenthal GmbH (DE) | 2010-11-17 | — | — | EP | disclosed |
| US-20100151028-A1 | CRUSH RESISTANT DELAYED-RELEASE DOSAGE FORMS | GRUNENTHAL GMBH (DE) | 2010-06-17 | — | — | US | disclosed |
| US-20090202634-A1 | PHARMACEUTICAL DOSAGE FORM | GRUNENTHAL GMBH (DE) | 2009-08-13 | — | — | US | disclosed |
| WO-2009092601-A1 | PHARMACEUTICAL DOSAGE FORM | Grünenthal GmbH (DE) | 2009-07-30 | — | — | WO | disclosed |
| US-20080311187-A1 | CRUSH RESISTAN DELAYED-RELEASE DOSAGE FORM | GRUNENTHAL GMBH (DE) | 2008-12-18 | — | — | US | disclosed |
| US-20060193914-A1 | Crush resistant delayed-release dosage forms | ENDO PHARMACEUTICALS, INC. | 2006-08-31 | — | — | US | disclosed |