Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 11/20 | 0.54 |
| ▸ | AKR1C2 | P52895 | 11/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL154696 | 0.85 | ALDH1A1 (0.65) | AKR1C3AKR1C2NPC1RAB9AKDM4E | |
| SCHEMBL1586234 | 0.85 | SMN1; SMN2 (0.59) | SMN1; SMN2AKR1C3AKR1C2KDM4EPOLB | |
| SCHEMBL31494905 | 0.85 | SMN1; SMN2 (0.59) | SMN1; SMN2AKR1C3AKR1C2KDM4EPOLB | |
| SCHEMBL6931977 | 0.83 | NPC1 (0.50) | SMN1; SMN2AKR1C3AKR1C2NPC1RAB9A | |
| SCHEMBL4216899 | 0.83 | KDM4E (0.56) | SMN1; SMN2AKR1C3AKR1C2NPC1RAB9A | |
| SCHEMBL383820 | 0.82 | ALDH1A1 (0.66) | SMN1; SMN2AKR1C3AKR1C2NPC1RAB9A | |
| SCHEMBL22129880 | 0.81 | KDM4E (0.67) | KDM4EALDH1A1HPGDCYP3A4MAPK1 | |
| SCHEMBL157100 | 0.81 | HTT (0.69) | SMN1; SMN2NPC1RAB9AKDM4EPOLB | |
| SCHEMBL10013752 | 0.80 | NPC1 (0.47) | SMN1; SMN2NPC1RAB9APOLBALDH1A1 | |
| Benzene SCHEMBL29227606 | 0.80 | ALDH1A1 (0.63) | SMN1; SMN2AKR1C3AKR1C2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4635949-A1 | SUBSTITUTED TETRAHYDROCYCLOPENTYL[C]PYRROLE DERIVATIVE, PREPARATION METHOD, INTERMEDIATE AND USE THEREOF | Jiangsu NHWA Pharmaceutical Co., Ltd (CN) | 2025-10-22 | — | — | EP | disclosed |
| CN-120081802-A | Heterocyclic substituted benzamide derivative and application thereof | 南华大学附属第一医院 | 2025-06-03 | — | — | CN | disclosed |
| WO-2024125395-A1 | SUBSTITUTED TETRAHYDROCYCLOPENTYL[C]PYRROLE DERIVATIVE, PREPARATION METHOD, INTERMEDIATE AND USE THEREOF | 江苏恩华药业股份有限公司 | 2024-06-20 | — | — | WO | disclosed |
| CN-113321604-B | Preparation method of beta-carotene | 万华化学集团股份有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-111138445-B | Method for preparing 5, 12-dioxaanthracene-6, 11-diketone compound by nickel catalysis | 浙江农林大学暨阳学院 | 2022-07-22 | — | — | CN | disclosed |
| CN-113321604-A | Preparation method of beta-carotene with high all-trans content | 万华化学集团股份有限公司 | 2021-08-31 | — | — | CN | disclosed |
| WO-2020130081-A1 | METHOD FOR PRODUCING 2-IODOSOBENZOIC ACIDS | 学校法人立命館 | 2020-06-25 | — | — | WO | disclosed |
| US-10662173-B2 | Indole and pyrrole compounds, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2020-05-26 | — | — | US | disclosed |
| CN-111138445-A | Method for preparing 5, 12-dioxaanthracene-6, 11-diketone compound by nickel catalysis | 浙江农林大学暨阳学院 | 2020-05-12 | — | — | CN | disclosed |
| CN-110092788-A | Substituted [1,2,4] triazol [1,5-a] pyrimidin-7-yl compound as PDE2 inhibitor | 达特神经科学(开曼)有限公司 | 2019-08-06 | — | — | CN | disclosed |
| US-4105664-A | Dibenz[b,f]oxepin derivatives | HOFFMANN-LA ROCHE INC. (US) | 1978-08-08 | — | — | US | disclosed |
| US-4100173-A | DEPRESSANTS, SCHIZOPHRENIA, TRANQUILIZERS | HOFFMANN-LA ROCHE INC. (US) | 1978-07-11 | — | — | US | disclosed |
| US-4091023-A | ANTISCHIZOPHRENIA AGENTS, TRANQUILIZERS | HOFFMANN-LA ROCHE INC. (US) | 1978-05-23 | — | — | US | disclosed |
| US-4044010-A | NEUROLEPTIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1977-08-23 | — | — | US | disclosed |
| US-4032525-A | CNS DEPRESSANTS, NEUROLEPTICS | HOFFMANN-LA ROCHE INC. (US) | 1977-06-28 | — | — | US | disclosed |
| US-4011222-A | NEUROLEPTIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1977-03-08 | — | — | US | disclosed |
| US-3996229-A | DEPRESSANTS, NEUROLEPTICS | HOFFMANN-LA ROCHE INC. (US) | 1976-12-07 | — | — | US | disclosed |
| US-3966737-A | NEUROLEPTIC | HOFFMANN-LA ROCHE INC. (US) | 1976-06-29 | — | — | US | disclosed |
| US-3954764-A | NEUROLEPTIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1976-05-04 | — | — | US | disclosed |
| US-3954769-A | NEUROLEPTIC AGENTS | HOFFMAN-LA ROCHE INC. (US) | 1976-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10662173-B2 | Indole and pyrrole compounds, a process for their preparation and pharmaceutical compositions containing them | RB1, IDO1, BCL2A1 | SMN1; SMN2 3448/4885AKR1C3 132/4885AKR1C2 259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.