SCHEMBL383820

SCHEMBL383820

COc1ccc(C(=O)O)c(C(=O)O)c1

nearest known ligand 0.66

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.66
SMN1; SMN2 Q16637 2/20 0.65
AKR1C3 P42330 9/20 0.59
AKR1C2 P52895 9/20 0.59
KDM4E B2RXH2 4/20 0.59
POLB P06746 2/20 0.59
NPC1 O15118 1/20 0.57
RAB9A P51151 1/20 0.57
GAA P10253 2/20 0.56
TDP1 Q9NUW8 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
CYP3A4 P08684 1/20 0.55
HPGD P15428 1/20 0.55
MAPK1 P28482 1/20 0.55
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
RXFP1 Q9HBX9 1/20 0.53
LMNA P02545 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL29227606 0.98 ALDH1A1 (0.63) ALDH1A1SMN1; SMN2AKR1C3AKR1C2KDM4E
SCHEMBL5307872 0.92 NPC1 (0.63) ALDH1A1SMN1; SMN2AKR1C3AKR1C2KDM4E
SCHEMBL4128750 0.90 ALDH1A1 (0.65) ALDH1A1SMN1; SMN2AKR1C3AKR1C2KDM4E
SCHEMBL3037245 0.90 ALDH1A1 (0.65) ALDH1A1SMN1; SMN2AKR1C3AKR1C2KDM4E
SCHEMBL27939607 0.89 CDC25B (0.66) ALDH1A1SMN1; SMN2AKR1C3AKR1C2KDM4E
SCHEMBL523820 0.88 POLB (0.63) ALDH1A1SMN1; SMN2AKR1C3AKR1C2KDM4E
SCHEMBL5736385 0.88 KDM4E (0.60) ALDH1A1SMN1; SMN2AKR1C3AKR1C2KDM4E
SCHEMBL1956889 0.88 KDM4E (0.60) ALDH1A1SMN1; SMN2AKR1C3AKR1C2KDM4E
SCHEMBL7016460 0.88 SMN1; SMN2 (0.57) ALDH1A1SMN1; SMN2AKR1C3AKR1C2KDM4E
SCHEMBL14608284 0.88 SMN1; SMN2 (0.57) ALDH1A1SMN1; SMN2AKR1C3AKR1C2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119119834-A Concrete composite floor for outdoor wet area and preparation method thereof 黄山精强建材股份有限公司 2024-12-13 CN claimed
CN-118341173-A Filter bag with welding agent material and preparation method thereof 江苏奥凯环境技术有限公司 2024-07-16 CN claimed
EP-3517553-B1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2023-11-08 EP claimed
CN-109749067-B Polyester resin with excellent flexibility for powder coating and preparation method thereof 安徽永利新材料科技有限公司 2021-01-26 CN claimed
EP-3135697-B1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2019-08-14 EP claimed
CN-1308604-A 2,3,5-substituted biphenyls useful in the treatment of insulin resistance and hyperglycemia AMERICAN HOME PROD (US) 2001-08-15 CN claimed
EP-4683934-A1 SYSTEM OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2026-01-28 EP disclosed
EP-4655355-A1 PHOTOACTIVE FLUORESCENT COMPOUNDS AND USE THEREOF FOR LABELING OF PROTEINS Eikon Therapeutics, Inc. (US) 2025-12-03 EP disclosed
EP-4596606-A1 CURABLE COMPOSITION Daicel Corporation (JP) 2025-08-06 EP disclosed
US-20250214921-A1 METHOD FOR PRODUCING CYCLIC DIKETONE COMPOUND KAO CORPORATION (JP) 2025-07-03 US disclosed
US-20250214920-A1 METHOD FOR PRODUCING CYCLIC DIKETONE COMPOUND KAO CORPORATION (JP) 2025-07-03 US disclosed
CN-119948083-A Curable composition 株式会社大赛璐 2025-05-06 CN disclosed
US-20250092020-A1 IDO/TDO Inhibitor GENERAL INCORPORATED ASSOCIATION PHARMA VALLEY PROJECT SUPPORTING ORGANIZATION (JP) 2025-03-20 US disclosed
US-3991042-A Basic azo dyestuffs containing a benzthiazole and a tetrahydroquinoline nucleus BAYER AKTIENGESELLSCHAFT (DT) 1976-11-09 US disclosed
US-3971807-A BENZINDOLE BAYER AKTIENGESELLSCHAFT (DT) 1976-07-27 US disclosed
US-3959310-A BENZINDOLE BAYER AKTIENGESELLSCHAFT (DT) 1976-05-25 US disclosed
US-3956264-A Basic azo dyestuffs having indolyl-methyleneamino substituent in the diazo component BAYER AKTIENGESELLSCHAFT (DT) 1976-05-11 US disclosed
US-3950347-A NAPHTHOLACTAM DYESTUFFS BAYER AKTIENGESELLSCHAFT (DT) 1976-04-13 US disclosed
US-3948877-A POLYACRYLONITRILE, ACID MODIFIED POLYESTERS OR POLYAMIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-04-06 US disclosed
US-3947477-A Process for the preparation of aminohydroxyanthraquinones BAYER AKTIENGESELLSCHAFT (DT) 1976-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214920-A1 METHOD FOR PRODUCING CYCLIC DIKETONE COMPOUND CYP4F2, DUOX1, BCKDK ALDH1A1 973/4885SMN1; SMN2 4175/4885AKR1C3 145/4885
US-20250214921-A1 METHOD FOR PRODUCING CYCLIC DIKETONE COMPOUND HSD17B7, HSD17B12, BCKDK ALDH1A1 699/4885SMN1; SMN2 4516/4885AKR1C3 68/4885
US-20250092020-A1 IDO/TDO Inhibitor IDO1, IDO2, TDO2 ALDH1A1 3331/4885SMN1; SMN2 1967/4885AKR1C3 534/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.