Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 3/20 | 0.36 |
| ▸ | ENPEP | Q07075 | 3/20 | 0.36 |
| ▸ | GABRP | O00591 | 2/20 | 0.34 |
| ▸ | GABRD | O14764 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.34 |
| ▸ | GABRE | P78334 | 2/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL117345 | 0.91 | LTA4H (0.37) | LTA4HALDH1A1CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL29071875 | 0.87 | LTA4H (0.42) | LTA4HCYP3A4HTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29071909 | 0.87 | LTA4H (0.42) | LTA4HCYP3A4HTTSMN1; SMN2 | |
| SCHEMBL144467 | 0.87 | AAK1 (0.36) | LTA4H | |
| Hydrochloric Acid SCHEMBL29071911 | 0.87 | LTA4H (0.42) | LTA4HCYP3A4HTTSMN1; SMN2 | |
| SCHEMBL22321345 | 0.86 | LTA4H (0.35) | LTA4HS1PR2S1PR1CYP2C19CYP3A4 | |
| SCHEMBL22321343 | 0.86 | LTA4H (0.35) | LTA4HS1PR2S1PR1CYP2C19CYP3A4 | |
| SCHEMBL5026306 | 0.85 | CYSLTR2 (0.37) | ALDH1A1CYP1A2CYP2D6TSHRCYP2C19 | |
| SCHEMBL9523633 | 0.85 | GAA (0.36) | ALDH1A1CYP1A2CYP2D6TSHRCYP2C19 | |
| SCHEMBL8122701 | 0.85 | GAA (0.36) | ALDH1A1CYP1A2CYP2D6TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2250171-A2 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | Achaogen, Inc. (US) | 2010-11-17 | — | — | EP | disclosed |
| WO-2009137130-A2 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2009-11-12 | — | — | WO | disclosed |