Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 7/20 | 0.34 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29666570 | 0.88 | AAK1 (0.35) | AAK1LTA4HCTSSCTSKPTPRC | |
| SCHEMBL3404476 | 0.87 | LTA4H (0.38) | LTA4H | |
| SCHEMBL117345 | 0.86 | LTA4H (0.37) | AAK1LTA4H | |
| Hydrochloric Acid SCHEMBL29071909 | 0.83 | LTA4H (0.42) | LTA4H | |
| SCHEMBL29071875 | 0.83 | LTA4H (0.42) | LTA4H | |
| Hydrochloric Acid SCHEMBL29071911 | 0.83 | LTA4H (0.42) | LTA4H | |
| SCHEMBL5727045 | 0.80 | CYP3A4 (0.36) | — | |
| SCHEMBL22321343 | 0.79 | LTA4H (0.35) | LTA4H | |
| SCHEMBL22321345 | 0.79 | LTA4H (0.35) | LTA4H | |
| SCHEMBL20212163 | 0.79 | SIGMAR1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | RECQL, BLVRB, NQO2 | AAK1 4159/4885LTA4H 1162/4885CTSS 888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.