Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | ALPI | P09923 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | XIAP | P98170 | 1/20 | 0.30 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3404476 | 0.91 | LTA4H (0.38) | LTA4HALDH1A1SMN1; SMN2CYP3A4HTT | |
| SCHEMBL144467 | 0.86 | AAK1 (0.36) | LTA4HAAK1 | |
| Hydrochloric Acid SCHEMBL29071909 | 0.86 | LTA4H (0.42) | LTA4HSMN1; SMN2CYP3A4HTT | |
| Hydrochloric Acid SCHEMBL29071911 | 0.86 | LTA4H (0.42) | LTA4HSMN1; SMN2CYP3A4HTT | |
| SCHEMBL29071875 | 0.86 | LTA4H (0.42) | LTA4HSMN1; SMN2CYP3A4HTT | |
| SCHEMBL5727045 | 0.83 | CYP3A4 (0.36) | SMYD2SMN1; SMN2CYP3A4HTT | |
| SCHEMBL28414419 | 0.83 | SMYD2 (0.32) | ALDH1A1SMYD2SMN1; SMN2CYP3A4HTT | |
| SCHEMBL22321345 | 0.82 | LTA4H (0.35) | LTA4HSMYD2SMN1; SMN2CYP3A4HTT | |
| SCHEMBL22321343 | 0.82 | LTA4H (0.35) | LTA4HSMYD2SMN1; SMN2CYP3A4HTT | |
| SCHEMBL20212163 | 0.82 | SIGMAR1 (0.34) | SMYD2SMN1; SMN2CYP3A4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | RECQL, BLVRB, NQO2 | LTA4H 1162/4885ALDH1A1 1678/4885SMYD2 4608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.