⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25329731 | 0.83 | ALOX5 (0.30) | — | |
| SCHEMBL13376481 | 0.77 | KDM4E (0.31) | — | |
| SCHEMBL23271933 | 0.73 | ALDH1A1 (0.44) | — | |
| SCHEMBL25329539 | 0.72 | — | — | |
| SCHEMBL19354011 | 0.72 | — | — | |
| SCHEMBL1057083 | 0.71 | — | — | |
| SCHEMBL13488480 | 0.71 | TAS1R3 (0.32) | — | |
| SCHEMBL25329013 | 0.70 | — | — | |
| SCHEMBL17480082 | 0.69 | TAS1R3 (0.31) | — | |
| SCHEMBL29581599 | 0.69 | SCN4A (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160256521-A1 | TOPICAL FORMULATIONS AND USES THEREOF | OCULAR TECHNOLOGIES SARL (CH) | 2016-09-08 | — | — | US | disclosed |
| US-9315447-B2 | Compositions and methods for the treatment of inflammation | A.T. Resolve Sarl (CH) | 2016-04-19 | — | — | US | disclosed |
| US-20150165048-A1 | TOPICAL FORMULATIONS AND USES THEREOF | SUN PHARMA GLOBAL FZE (AE) | 2015-06-18 | — | — | US | disclosed |
| US-20140275247-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATION | A.T. Resolve Sarl (CH) | 2014-09-18 | — | — | US | disclosed |
| US-8673881-B2 | Compositions and methods for the treatment of inflammation | A.T. Resolve Sarl (CH) | 2014-03-18 | — | — | US | disclosed |
| US-20120122816-A1 | COMPOSITIONS AND METHODS FOR ORGAN PRESERVATION | RESOLVYX PHARMACEUTICALS, INC. (US) | 2012-05-17 | — | — | US | disclosed |
| US-20120101061-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATION | A.T. Resolve Sarl (CH) | 2012-04-26 | — | — | US | disclosed |
| US-20110190242-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATORY DISEASE | RESOLVYX PHARMACEUTICALS, INC. (US) | 2011-08-04 | — | — | US | disclosed |
| US-20100035989-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF MUCOSITIS | RESOLVYX PHARMACEUTICALS, INC. | 2010-02-11 | — | — | US | disclosed |
| US-20090137527-A1 | Compositions and methods for modulating immune function | RESOLVYX PHARMACEUTICALS, INC. (US) | 2009-05-28 | — | — | US | disclosed |
| US-20090118243-A1 | Compositions and methods for the treatment of ophthalmic conditions | RESOLVYX PHARMACEUTICALS, INC. (US) | 2009-05-07 | — | — | US | disclosed |
| US-20080161274-A1 | Compounds and methods for inhibition of bone loss | RESOLVYX PHARMACEUTICALS, INC. (US) | 2008-07-03 | — | — | US | disclosed |
| US-20080161275-A1 | Compositions and methods for the treatment of inflammatory disease | RESOLVYX PHARMACEUTICALS, INC. (US) | 2008-07-03 | — | — | US | disclosed |
| US-20070254897-A1 | Compositions and methods for the treatment of cardiovascular disease | RESOLVYX PHARMACEUTICALS, INC. (US) | 2007-11-01 | — | — | US | disclosed |