Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL936764 | 0.89 | KDM4E (0.56) | SCDDCTPP1 | |
| SCHEMBL27654400 | 0.86 | SCD (0.47) | SCDDCTPP1 | |
| SCHEMBL27654526 | 0.86 | SCD (0.47) | SCDDCTPP1 | |
| SCHEMBL27633683 | 0.85 | SCD (0.48) | SCDDCTPP1 | |
| SCHEMBL936746 | 0.83 | RBP4 (0.60) | SCDDCTPP1 | |
| SCHEMBL27634139 | 0.81 | HTR1A (0.52) | SCDDCTPP1 | |
| SCHEMBL1817020 | 0.80 | SCD (0.49) | SCDDCTPP1 | |
| SCHEMBL936973 | 0.77 | SCD (0.49) | SCDDCTPP1 | |
| SCHEMBL937341 | 0.77 | FAAH (0.50) | SCDDCTPP1 | |
| SCHEMBL935839 | 0.76 | SCD (0.77) | SCDDCTPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100558713-C | Pyridazine derivatives and their use as therapeutic agents | XENON PHARMACEUTICALS INC (CA) | 2009-11-11 | — | — | CN | claimed |
| CN-1829698-A | Pyridazine derivatives and their use as therapeutic agents | XENON PHARMACEUTICALS INC (CA) | 2006-09-06 | — | — | CN | claimed |
| EP-2257291-A2 | PYRIDAZINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS IN THE TREATMENT OF SKIN DISORDERS | Xenon Pharmaceuticals Inc. (CA) | 2010-12-08 | — | — | EP | disclosed |
| CN-100558713-C | Pyridazine derivatives and their use as therapeutic agents | XENON PHARMACEUTICALS INC (CA) | 2009-11-11 | — | — | CN | disclosed |
| WO-2009106991-A2 | PYRIDAZINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2009-09-03 | — | — | WO | disclosed |
| CN-1829698-A | Pyridazine derivatives and their use as therapeutic agents | XENON PHARMACEUTICALS INC (CA) | 2006-09-06 | — | — | CN | disclosed |