Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.52 |
| ▸ | PI4KA | P42356 | 2/20 | 0.47 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.47 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.47 |
| ▸ | AHCY | P23526 | 3/20 | 0.46 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.44 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.44 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.44 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.44 |
| ▸ | GAPDH | P04406 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | STAT6 | P42226 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3408365 | 0.87 | ADORA2A (0.54) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL3414697 | 0.84 | ADORA2A (0.52) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL8672664 | 0.80 | ADORA2A (0.67) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL6299609 | 0.79 | ADORA2A (0.54) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL6864727 | 0.77 | ADORA2A (0.54) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL3409866 | 0.76 | ADA (0.51) | ADORA2AADORA3EHMT1SMN1; SMN2ADA | |
| SCHEMBL20053490 | 0.76 | ADORA2A (0.61) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL10439705 | 0.75 | ADORA2A (0.54) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL11703712 | 0.74 | ADORA2A (0.54) | ADORA2AADORA3AHCYADORA2BADORA1 | |
| SCHEMBL3411985 | 0.74 | ADORA2A (0.53) | ADORA2AADORA3AHCYEHMT1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1878470-B1 | Skin depigmentation method | OREAL (FR) | 2009-03-11 | — | — | EP | claimed |
| EP-1878470-A1 | Skin depigmentation method | L'Oréal (FR) | 2008-01-16 | — | — | EP | claimed |
| US-20070258921-A1 | PROCESS FOR DEPIGMENTING THE SKIN | L'OREAL (FR) | 2007-11-08 | — | — | US | claimed |
| EP-2204154-B1 | Association of monosaccharides and adenosine and its cosmetic use | ORÉAL L (FR) | 2016-10-12 | — | — | EP | disclosed |
| EP-2204154-A1 | Association of monosaccharides and adenosine and its cosmetic use | L'OREAL (FR) | 2010-07-07 | — | — | EP | disclosed |
| US-20100168049-A1 | COMBINATION OF MONOSACCHARIDES AND ADENOSINE AND USE THEREOF | L'OREAL (FR) | 2010-07-01 | — | — | US | disclosed |
| EP-1878470-B1 | Skin depigmentation method | OREAL (FR) | 2009-03-11 | — | — | EP | disclosed |
| EP-1878470-A1 | Skin depigmentation method | L'Oréal (FR) | 2008-01-16 | — | — | EP | disclosed |
| US-20070258921-A1 | PROCESS FOR DEPIGMENTING THE SKIN | L'OREAL (FR) | 2007-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070258921-A1 | PROCESS FOR DEPIGMENTING THE SKIN | TYR, CUTA, NQO1 | ADORA2A 3810/4885ADORA3 4081/4885PI4KA 3626/4885 |
| US-20100168049-A1 | COMBINATION OF MONOSACCHARIDES AND ADENOSINE AND USE THEREOF | ADORA2A, ADORA1, ADORA3 | ADORA2A 1/4885ADORA3 3/4885PI4KA 2407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.