Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13862032 | 0.78 | PIK3CG (0.32) | PIK3CAPIK3CG | |
| SCHEMBL5954348 | 0.75 | PDGFRB (0.31) | PIK3CA | |
| SCHEMBL2516569 | 0.71 | PIK3CG (0.46) | PIK3CAPIK3CDPIK3CG | |
| SCHEMBL3486298 | 0.70 | PIK3CA (0.40) | PIK3CA | |
| SCHEMBL254022 | 0.69 | TTK (0.42) | PIK3CA | |
| SCHEMBL3394855 | 0.69 | KDM4E (0.30) | — | |
| SCHEMBL3405758 | 0.69 | RAB9A (0.35) | — | |
| SCHEMBL2517479 | 0.69 | PIK3CG (0.43) | PIK3CAPIK3CG | |
| SCHEMBL2516313 | 0.69 | PIK3CG (0.45) | PIK3CAPIK3CG | |
| SCHEMBL17856992 | 0.69 | DYRK1A (0.53) | PIK3CAPIK3CDPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012003338-A1 | COMBINATION OF A cMET INHIBITOR AND AN ANTIBODY TO HGF AND/OR cMET | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-01-05 | — | — | WO | disclosed |
| WO-2010019899-A1 | cMET INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |