SCHEMBL3407010

SCHEMBL3407010

CC=CC(=O)OCCC[SiH2]C(F)F

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.43
HCAR2 Q8TDS4 4/20 0.39
MAPT P10636 1/20 0.34
RAB9A P51151 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
TSHR P16473 2/20 0.33
HPGD P15428 1/20 0.33
ALDH1A1 P00352 1/20 0.32
CYP3A4 P08684 1/20 0.32
GSTP1 P09211 1/20 0.31
APP P05067 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26094547 0.95 ATM (0.42) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL26095399 0.94 HCAR2 (0.41) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL26094923 0.94 HCAR2 (0.41) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL26095636 0.94 HCAR2 (0.41) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL26092798 0.94 HCAR2 (0.41) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL26095442 0.94 HCAR2 (0.41) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL26095434 0.94 HCAR2 (0.41) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL26094591 0.94 HCAR2 (0.41) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL26092836 0.94 HCAR2 (0.41) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL26093455 0.94 HCAR2 (0.41) ATMHCAR2MAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2011834-B1 CURABLE COMPOSITION KANEKA CORP (JP) 2012-07-25 EP claimed
US-20230134471-A1 METHOD FOR PRODUCING (METH)ACRYLOXY GROUP-CONTAINING ORGANOSILICON COMPOUNDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-04 US disclosed
EP-4174076-A1 METHOD FOR PRODUCING (METH)ACRYLOXY GROUP-CONTAINING ORGANOSILICON COMPOUNDS Shin-Etsu Chemical Co., Ltd. (JP) 2023-05-03 EP disclosed
CN-116041382-A Method for producing organosilicon compounds containing (meth) acryloxy groups 信越化学工业株式会社 2023-05-02 CN disclosed
US-11377455-B2 Preparation of organosilicon compound having (meth)acryloyloxy group SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-07-05 US disclosed
US-20210139515-A1 Preparation of Organosilicon Compound Having (Meth)acryloyloxy Group SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-05-13 US disclosed
EP-3819301-A1 PREPARATION OF ORGANOSILICON COMPOUND HAVING (METH)ACRYLOYLOXY GROUP Shin-Etsu Chemical Co., Ltd. (JP) 2021-05-12 EP disclosed
CN-105392845-B Photocurable composition 思美定株式会社 2020-10-20 CN disclosed
EP-3081612-B1 PHOTOCURABLE COMPOSITION HAVING ADHESIVE PROPERTIES CEMEDINE CO LTD (JP) 2018-11-14 EP disclosed
US-9718999-B2 Photocurable composition having adhesive properties CEMEDINE CO., LTD (JP) 2017-08-01 US disclosed
US-20160312089-A1 PHOTOCURABLE COMPOSITION HAVING ADHESIVE PROPERTIES CEMEDINE CO., LTD. (JP) 2016-10-27 US disclosed
EP-3081612-A1 PHOTOCURABLE COMPOSITION HAVING ADHESIVE PROPERTIES Cemedine Co., Ltd. (JP) 2016-10-19 EP disclosed
US-20160152783-A1 PHOTOCURABLE COMPOSITION CEMEDINE CO., LTD. (JP) 2016-06-02 US disclosed
EP-3023462-A1 PHOTOCURABLE COMPOSITION Cemedine Co., Ltd. (JP) 2016-05-25 EP disclosed
EP-2011834-B1 CURABLE COMPOSITION KANEKA CORP (JP) 2012-07-25 EP disclosed
US-7772332-B2 organotin-free catalyst; fluorosilane catalyst and an amine or aminoalkylsiloxane coupler used together for high curing of a polymer with a reactive silicon group; polymer is hydrosilylated polyether, polyisobutylene, or polyacrylate; sealant, adhesive; oil resistance; elasticity KANEKA CORPORATION (JP) 2010-08-10 US disclosed
US-20090069505-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2009-03-12 US disclosed
EP-2011834-A1 CURABLE COMPOSITION Kaneka Corporation (JP) 2009-01-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11377455-B2 Preparation of organosilicon compound having (meth)acryloyloxy group H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, MMAB, ACR ATM 157/4885HCAR2 2645/4885MAPT 2971/4885
US-20210139515-A1 Preparation of Organosilicon Compound Having (Meth)acryloyloxy Group H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, MMAB, ACR ATM 163/4885HCAR2 2578/4885MAPT 3041/4885
US-20230134471-A1 METHOD FOR PRODUCING (METH)ACRYLOXY GROUP-CONTAINING ORGANOSILICON COMPOUNDS HM13, RPS13, GRHPR ATM 934/4885HCAR2 339/4885MAPT 4369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.