Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F12 | P00748 | 8/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2248693 | 0.85 | ALDH1A1 (0.37) | F12CNR2F2PDE10ACDK2 | |
| SCHEMBL2248670 | 0.77 | ITGB3 (0.36) | CNR2HSP90AA1 | |
| SCHEMBL2249737 | 0.75 | FLT3 (0.40) | CNR2MAPK1CCNE1CDK2HSP90AA1 | |
| SCHEMBL3405724 | 0.74 | CNR2 (0.32) | CNR2MAPK1PDE10A | |
| SCHEMBL2246328 | 0.72 | GPR119 (0.45) | — | |
| SCHEMBL2248657 | 0.72 | GPR119 (0.41) | NPC1RAB9A | |
| SCHEMBL2248264 | 0.70 | GPR119 (0.42) | HSP90AA1 | |
| SCHEMBL13003704 | 0.70 | HSP90AA1 (0.44) | PDE10AHSP90AA1NPC1RAB9A | |
| SCHEMBL2249696 | 0.69 | PDGFRB (0.47) | NPC1RAB9A | |
| SCHEMBL2181393 | 0.69 | ESR1 (0.41) | HSP90AA1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252613-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM, LLC (BM) | 2010-11-24 | — | — | EP | claimed |
| WO-2009105717-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2009-08-27 | — | — | WO | claimed |