SCHEMBL340718

SCHEMBL340718

CCCC[SiH](CCCC)OCC

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
LMNA P02545 1/20 0.33
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3482469 0.95 LMNA (0.30) TSHRLMNA
SCHEMBL4623058 0.92 TSHR (0.37) TSHRLMNATHRB
SCHEMBL28616633 0.89 TSHR (0.42) TSHRLMNATHRB
SCHEMBL7056918 0.89 TSHR (0.42) TSHRLMNATHRB
SCHEMBL6057151 0.89 TSHR (0.42) TSHRLMNATHRB
SCHEMBL3482686 0.89 LMNA (0.30) TSHRLMNA
SCHEMBL6303418 0.83 TSHR (0.42) TSHRLMNATHRB
SCHEMBL341004 0.81
SCHEMBL864210 0.80 ADRB2 (0.39) TSHRLMNATHRB
SCHEMBL3481443 0.80 ADRB2 (0.33) TSHRLMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117924346-A Multi-sulfur-containing silane coupling agent and preparation method thereof 江西宏柏新材料股份有限公司 2024-04-26 CN claimed
US-20210354518-A1 TIRE WITH REDUCED CAVITY NOISE HANKOOK TIRE CO., LTD. (KR) 2021-11-18 US claimed
EP-3315319-B1 TIRE WITH REDUCED CAVITY NOISE HANKOOK TIRE CO LTD (KR) 2020-06-24 EP claimed
CN-107972418-B Cavity noise reduction tire 韩国轮胎株式会社 2020-04-07 CN claimed
EP-3315319-A1 TIRE WITH REDUCED CAVITY NOISE Hankook Tire Co., Ltd. (KR) 2018-05-02 EP claimed
US-20180111428-A1 TIRE WITH REDUCED CAVITY NOISE HANKOOK TIRE CO., LTD. (KR) 2018-04-26 US claimed
US-20100137525-A1 Catalyst composition for hydrogenation and their use for hydrogenation conjugated diene polymer CHI-MEI CORPORATION 2010-06-03 US claimed
US-20080171653-A1 Catalyst composition for hydrogenation and their use for hydrogenation conjugated diene polymer CHI-MEI CORPORATION 2008-07-17 US claimed
CN-1130382-C Catalyst composition for hydrogenation of conjugated diene polymer and process for hydrogenation of the polymer INST IND TECHNOLOGY (CN) 2003-12-10 CN claimed
CN-1324867-A Catalyst composition for hydrogenation of conjugated diene polymer and process for hydrogenation of the polymer INST OF IND TECHN (CN) 2001-12-05 CN claimed
US-6313230-B1 HYDROGENATING CONJUGATED DIENE POLYMERS IN PRESENCE OF HYDROGEN AND A HYDROGENATION CATALYST FORMULATION COMPRISING TITANIUM COMPOUND, SILYL HYDRIDE COMPOUND, POLYSILOXANE, SILAZAN COMPOUND, AND METALLIC COMPOUND INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2001-11-06 US claimed
US-12371451-B2 Inorganic porous carrier and method for producing nucleic acids using same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2025-07-29 US disclosed
CN-117924346-A Multi-sulfur-containing silane coupling agent and preparation method thereof 江西宏柏新材料股份有限公司 2024-04-26 CN disclosed
EP-3507104-B1 PRODUCTION OF CIS-1,4-POLYDIENES WITH MULTIPLE SILANE FUNCTIONAL GROUPS PREPARED BYIN-SITU BRIDGESTONE CORP (JP) 2024-03-27 EP disclosed
EP-4056604-B1 METHOD FOR PRODUCING COPOLYMER OF 1,3,7-OCTATRIENE AND STYRENE KURARAY CO (JP) 2023-08-02 EP disclosed
WO-2000052068-A1 PROCESS FOR PRODUCING POLYETHYLENE EASTMAN CHEMICAL COMPANY (US) 2000-09-08 WO disclosed
US-5624680-A SKIN ABSORPTION OF DRUGS WITH POLYETHERSILOXANE BLOCK COPOLYMERS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1997-04-29 US disclosed
US-5554706-A LOW TEMPERATURE LIQUID CRYSTALS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1996-09-10 US disclosed
EP-0710688-A1 HYDROXYSILYL-TERMINATED POLYOXYETHYLENE COMPOUND, QUATERNARY-SALT-TERMINATED BLOCK COPOLYMER, AND PERCUTANEOUS ABSORPTION PROMOTER SAGAMI CHEMICAL RESEARCH CENTER (JP) 1996-05-08 EP disclosed
EP-0695770-A1 COPOLYMER HAVING LIQUID CRYSTAL GROUP IN THE SIDE CHAIN SAGAMI CHEMICAL RESEARCH CENTER (JP) 1996-02-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12371451-B2 Inorganic porous carrier and method for producing nucleic acids using same SLCO2A1, SLCO2B1, SLCO4C1 TSHR 3999/4885LMNA 195/4885THRB 3868/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.