Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1598666 | 0.82 | ALDH1A1 (0.49) | TDP1ATML3MBTL1MEN1KMT2A | |
| SCHEMBL16732035 | 0.81 | TSHR (0.50) | TDP1ATML3MBTL1KMT2AELANE | |
| SCHEMBL1598707 | 0.80 | TDP1 (0.51) | TDP1ATML3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL727949 | 0.79 | ELANE (0.59) | TDP1ATML3MBTL1ELANECYP3A4 | |
| SCHEMBL26565550 | 0.79 | MTNR1A (0.44) | ATML3MBTL1MEN1KMT2A | |
| SCHEMBL4632631 | 0.79 | RAB9A (0.49) | TDP1L3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9647917 | 0.78 | CHRM1 (0.49) | TDP1ATML3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL16732380 | 0.78 | TDP1 (0.48) | TDP1ATML3MBTL1ELANESMN1; SMN2 | |
| SCHEMBL2021749 | 0.78 | HCAR2 (0.46) | TDP1ATML3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL1834386 | 0.78 | ELANE (0.55) | TDP1L3MBTL1MEN1KMT2AELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010051044-A1 | UNIQUE DUAL-ACTION THERAPEUTICS | UNIVERSITY OF MEDICINE AND DENTISTRY (US) | 2010-05-06 | — | — | WO | claimed |