Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15638381 | 0.79 | RAB9A (0.54) | GAAMAPTSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL15661401 | 0.79 | MAPT (0.53) | GAAMAPTSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL5043930 | 0.75 | LMNA (0.48) | GAAMAPTSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL3815000 | 0.74 | MAPT (0.56) | GAAMAPTSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL6846903 | 0.74 | MAPT (0.56) | GAAMAPTSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL11787009 | 0.72 | SMN1; SMN2 (0.45) | GAAMAPTSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL8710363 | 0.72 | RAB9A (0.51) | GAAMAPTSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL219147 | 0.72 | KDM4E (0.66) | GAAMAPTSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL1772808 | 0.72 | SMN1; SMN2 (0.58) | GAAMAPTSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL11787025 | 0.71 | PEPD (0.47) | MAPTSMN1; SMN2ALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139829-A1 | N-HETEROCYCLIC CARBENE (NHC) CATALYZED SYNTHESIS OF HYDROXAMIC ACIDS | Agency for Science, Technology and Research (SG) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008115153-A1 | N-HETEROCYCLIC CARBENE (NHC) CATALYZED SYNTHESIS OF HYDROXAMIC ACIDS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2008-09-25 | — | — | WO | disclosed |